2022 Fiscal Year Final Research Report
Explanation of neural plasticity in the corticospinal pathway through the use of repetitive peripheral magnetic stimulation
Project/Area Number |
20K19428
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Research Category |
Grant-in-Aid for Early-Career Scientists
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Allocation Type | Multi-year Fund |
Review Section |
Basic Section 59010:Rehabilitation science-related
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Research Institution | Fukushima Medical University (2022) Niigata University of Health and Welfare (2020-2021) |
Principal Investigator |
Asao Akihiko 福島県立医科大学, 保健科学部, 講師 (40780268)
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Project Period (FY) |
2020-04-01 – 2023-03-31
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Keywords | 末梢性磁気刺激 / 神経リハビリテーション / 皮質脊髄路 / 運動イメージ |
Outline of Final Research Achievements |
The present results demonstrate that interventions lasting over 10 minutes of repetitive peripheral magnetic stimulation (rPMS) combined with motor imagery enhance corticospinal excitability. Furthermore, a 20-minute intervention of this combination elicits greater changes in corticospinal excitability compared to rPMS alone in healthy participants. Conversely, these interventions might not affect the corticospinal excitability of antagonist muscles. When applying rPMS through hand splint materials, the stimulus intensity should be set higher than the threshold that clearly induces movement caused by rPMS. Moreover, rPMS may modulate spinal reflex excitability similar to neuromuscular electrical stimulation. Therefore, further investigation into stimulus parameters of rPMS in spinal reflex circuits is warranted.
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Free Research Field |
リハビリテーション科学
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Academic Significance and Societal Importance of the Research Achievements |
本研究により,運動イメージを組み合わせた反復末梢性磁気刺激は10分間以上の介入を反復することで皮質脊髄路の興奮性を増大させることが明らかとなった.本研究は健常者を対象とした基礎的な知見であるが,脳卒中などのリハビリテーションへと臨床応用において介入時間の設定に示唆を与える.また,スプリント装具上からの反復末梢性磁気刺激という新たなリハビリテーションの提案となる.
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