2021 Fiscal Year Research-status Report
Glia and migraine: integrative analysis of slow EEG and functional MRI
Project/Area Number |
20K21573
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Research Institution | Kyoto University |
Principal Investigator |
池田 昭夫 京都大学, 医学研究科, 特定教授 (90212761)
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Co-Investigator(Kenkyū-buntansha) |
澤本 伸克 京都大学, 医学研究科, 教授 (90397547)
美馬 達哉 立命館大学, 先端総合学術研究科, 教授 (20324618)
松橋 眞生 京都大学, 医学研究科, 特定准教授 (40456885)
荒川 芳輝 京都大学, 医学研究科, 講師 (20378649)
人見 健文 京都大学, 医学研究科, 講師 (50402904)
宇佐美 清英 京都大学, 医学研究科, 特定助教 (20829204)
山尾 幸広 京都大学, 医学研究科, 助教 (90736810)
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Project Period (FY) |
2020-07-30 – 2023-03-31
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Keywords | 片頭痛 / 頭痛 / グリア細胞 / wide-band EEG / EEG-fMRI |
Outline of Annual Research Achievements |
(研究の具体的内容) 成果1:広域周波帯脳波(wide-band EEG): 前兆のある片頭痛(MA),前兆のない片頭痛(MO)と頭痛専門医が確定診断し,臨床上の必要から脳波検査を施行した143人の患者において,患者の臨床上のプロファイルとそれらの脳波解析結果(脳波通常判読で用いる時定数0.3秒,および緩電位を捉える時定数2秒を用いた判読)との関連を解析した.その結果,①MA/MOの差は明らかでなかったが,徐波がみられ,年齢依存性に出現部位が後頭部から側頭部に移っていること,②有症状期や家族歴のある群で,それぞれ発作間欠期,家族歴のない群に比し,後頭部に緩電位(1秒あたり1周期未満の徐波でグリア活動との関連が考察される)が検出されることを見出し,学会で報告した.成果2:運動症状を伴う重症型の片麻痺性片頭痛(HM)での遺伝子変異の有無や脳波変化に関するデータの蓄積も行った.成果3:脳波-機能的MRI同時記録(EEG-fMRI): 上記の脳波変化の脳内起源を,深部を含めて明らかにするために本記録を行うことを計画し,倫理委員会審査の承認を得て機器のセットアップ,テストランを行った. (研究の意義・重要性) 確実な片頭痛診断例において脳波専門医の判読による時定数2秒での頭皮上脳波異常を多数例で検討を行うことができ,片頭痛の疾患バイオマーカーとしての脳波異常の意義を緩電位の新しい視点から検討できた.さらにEEG-fMRIについては片頭痛脳波変化の起源を探る新手法を展開する礎を築けた.
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Current Status of Research Progress |
Current Status of Research Progress
1: Research has progressed more than it was originally planned.
Reason
COVID-19に対する各種規制により,EEG-fMRI研究の進展は遅れていたが,年度末に実際の患者においての記録が可能な準備が整った.また,wide-band EEG研究に関しては学会発表も行って他分野研究者からの意見も得ることができ,論文化できる状態になった.
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Strategy for Future Research Activity |
Wide-band EEGに関しては,MA/MOの脳波変化については現状で論文化を進めるとともに,徐波以外のデータ解析,あるいは本データを二次利用した研究を検討する.HMやEEG-fMRIに関しては患者のリクルートとデータ解析を進め,てんかんとの病態の異同も含めて検討していく.
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Causes of Carryover |
COVID-19に対する国内の各種規制の影響で予定していた出張がなくなったため.次年度は規制緩和が予想され,他分野との交流のためにも学会に参加を含む出張を行い,今後の共同研究のために研究者との交流を含めた基盤作りを行う.
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Research Products
(202 results)
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[Journal Article] Enhanced phase-amplitude coupling of human electrocorticography selectively in the posterior cortical region during rapid eye movement sleep2022
Author(s)
Jumpei Togawa, Riki Matsumoto, Kiyohide Usami, Masao Matsuhashi, Morito Inouchi, Katsuya Kobayashi, Takefumi Hitomi, Takuro Nakae, Akihiro SHimotake, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
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Journal Title
Cerebral cortex
Volume: 33
Pages: 486_496
DOI
Peer Reviewed
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[Journal Article] Two types of clinical ictal direct current shifts endorsed by waveform property: A cluster analysis2022
Author(s)
Shunsuke Kajikawa, Masao Matsuhashi, Katsuya Kobayashi, Takefumi Hitomi, Masako Daifu-Kobayashi, Tamaki Kobayashi, Yukihiro Yamao, Takayuki Kikuchi, Takayuki Yoshida, Takeharu Kunieda, Riki Matsumoto, Akiyoshi Kakita, Takao Namiki, Ichiro Tsuda, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
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Journal Title
Clin Neurophysiol
Volume: 137
Pages: 113-121
Peer Reviewed
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[Journal Article] A Nationwide Questionnaire Survey on Awake Craniotomy in Japan.2022
Author(s)
Kawata M, Fukui A, Mineharu Y, Kikuchi T, Yamao Y, Yamamoto Hattori E, Shiraki A, Mizota T, Furukawa K, Miyamoto S, Yonezawa A, Arakawa Y.
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Journal Title
Neurol Med Chir (Tokyo)
Volume: 印刷中
Pages: -
DOI
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[Journal Article] Cortico-cortical evoked potential by single-pulse electrical stimulation is a generally safe prcedure2021
Author(s)
Katsuya Kobayashi, Riki Matsumoto, Kiyohide Usami, Masao Matsuhashi, Akihiro Shimotake, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
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Journal Title
Clin Neurophysiol
Volume: 132
Pages: 1033-1040
DOI
Peer Reviewed
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[Journal Article] The initial impact of the SARS‐CoV‐2 pandemic on epilepsy research2021
Author(s)
Nancy Volkers, Samuel Wiebe, Ali Akbar Asadi‐Pooya, Ganna Balagura, Patricia G?mez‐Iglesias, Alla Guekht, Julie Hall, Akio Ikeda, Nathalie Jett?, Nirmeen A, Kishk, Peter Murphy, Emilio Perucca, Juan Carlos P?rez‐Poveda, Emmanuel O Sanya, Eugen Trinka, Dong Zhou, J Helen Cross
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Journal Title
Epilepsia Open
Volume: 6
Pages: 255-265
DOI
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Effects of propofol on cortico-cortical evoked potentials in the dorsal language white matter pathway2021
Author(s)
Yukihiro Yamao, Riki Matsumoto, Takeharu Kunieda, Takuro Nakae, Sei Nishida, Rika Inano, Sumiya Shibata, Takayuki Kikuchi, Yoshiki Arakawa, Kazumichi Yoshida, Akio Ikeda, Susumu Miyamoto
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Journal Title
Clin Neurophysiol
Volume: 132
Pages: 1919-1926
DOI
Peer Reviewed
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[Journal Article] Epilepsy care during the COVID-19 pandemic2021
Author(s)
J Helen Cross, Churl-Su Kwon, Ali Asadi-Pooya, Ganna Balagura, Patricia G?mez Iglesias, Alla Guekht, Julie Hall, Akio Ikeda, Nirmeen Kishk, Peter Murphy, Najib Kissani, Yahya Naji, Emilio Perucca,Juan Carlos Perez Poveda, Emanuel Sanya, Eugen Trinka, Dong Zhou, Samuel Wiebe, Nathalie Jette
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Journal Title
Epilepsia
Volume: 62
Pages: 2322-2332
DOI
Peer Reviewed / Int'l Joint Research
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[Journal Article] A Biomarker for Benign Adult Familial Myoclonus Epilepsy: High-Frequency Activities in Giant Somatosensory Evoked Potentials2021
Author(s)
Maya Tojima, Takefumi Hitomi, Masao Matsuhashi, Shuichiro Neshige, Kiyohide Usami, Kazuki Oi, Katsuya Kobayashi, Hirofumi Takeyama, Akihiro Shimotake, Ryosuke Takahashi, Akio Ikeda
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Journal Title
Mov Disord
Volume: 36
Pages: 2335-2345
DOI
Peer Reviewed
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[Journal Article] A role of aging in the progression of cortical excitability in BAFME1 patients2021
Author(s)
Shuichiro Neshige, Takefumi Hitomi, Maya Tojima, Kazuki Oi, Katsuya Kobayashi, Masao Matsuhashi, Akihiro Shimotake, Riki Matsumoto, Masutaro Kanda, Hirofumi Maruyama, Hiroyuki Ishiura, Shoji Tsuji, Ryosuke Takahashi, Akio Ikeda
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Journal Title
Mov Disord
Volume: 36
Pages: 2446-2448
DOI
Peer Reviewed
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[Journal Article] Effects of a stable concentration of propofol upon interictal high-frequency oscillations in drug-resistant epilepsy2021
Author(s)
Taku Inada, Katsuya Kobayashi, Takayuki Kikuchi, Masao Matsuhashi, Riki Matsumoto, Yuki Takahashi, Takuro Nakae, Sumiya Shibata, Yukihiro Yamao, Masako Daifu, Jumpei Togawa, Kazumichi Yoshida, Takeharu Kunieda, Kobayashi K, Akio Ikeda, Susumu Miyamoto
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Journal Title
Epileptic Disord
Volume: 23
Pages: 299-312
DOI
Peer Reviewed
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[Journal Article] Frequency-Dependent Cortical Interactions during Semantic Processing: An Electrocorticogram Cross-spectrum Analysis Using a Semantic Space Model2021
Author(s)
Naoyuki Sato, Riki Matsumoto, Akihiro Shimotake, Masao Matsuhashi, Mayumi Otani, Takayuki Kikuchi, Takeharu Kunieda, Hiroaki Mizuhara, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
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Journal Title
Cereb Cortex
Volume: 31
Pages: 4329-4339
DOI
Peer Reviewed
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[Journal Article] The initial impact of the SARS-CoV-2 pandemic on epilepsy research2021
Author(s)
Nancy Volkers, Samuel Wiebe, Ali Akbar Asadi-Pooya, Ganna Balagura, Patricia G?mez-Iglesias, Alla Guekht, Julie Hall, Akio Ikeda, Nathalie Jett?, Nirmeen A Kishk, Peter Murphy, Emilio Perucca, Juan Carlos P?rez-Poveda, Emmanuel O Sanya, Eugen Trinka, Dong Zhou, J Helen Cross
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Journal Title
Epilepsia Open
Volume: 6
Pages: 255-265
DOI
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Evidence for a deep, distributed and dynamic code for animacy in human ventral anterior temporal cortex2021
Author(s)
Timothy T Rogers, Christopher R Cox, Qihong Lu, Akihiro Shimotake, Takayuki Kikuchi, Takeharu Kunieda, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda, Riki Matsumoto, Matthew A Lambon Ralph
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Journal Title
Elife
Volume: 10
Pages: e66276
DOI
Peer Reviewed
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[Journal Article] Importance of access to epilepsy monitoring units during the COVID-19 pandemic: Consensus statement of the International League against epilepsy and the International Federation of Clinical Neurophysiology2021
Author(s)
S?ndor Beniczky, Aatif Husain, Akio Ikeda, Haifa Alabri, J Helen Cross, Jo Wilmshurst, Margitta Seeck, Niels Focke, Patricia Braga, Samuel Wiebe, Stephan Schuele, Eugen Trinka
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Journal Title
Clin Neurophysiol
Volume: 132
Pages: 2248-2250
DOI
Peer Reviewed / Int'l Joint Research
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[Journal Article] Importance of access to epilepsy monitoring units during the COVID-19 pandemic: consensus statement of the International League Against Epilepsy and the International Federation of Clinical Neurophysiology2021
Author(s)
S?ndor Beniczky, Aatif Husain, Akio Ikeda, Haifa Alabri, J Helen Cross, Jo Wilmshurst, Margitta Seeck, Niels Focke, Patricia Braga, Samuel Wiebe, Stephan Schuele, Eugen Trinka
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Journal Title
Epileptic Disord
Volume: 23
Pages: 533-536
DOI
Peer Reviewed / Int'l Joint Research
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[Journal Article] Evaluation of movement and brain activity2021
Author(s)
Mark Hallett, Lourdes M DelRosso, Rodger Elble, Raffaele Ferri, Fay B Horak, Stephan Lehericy, Martina Mancini, Masao Matsuhashi, Riki Matsumoto, Muthuraman Muthuraman, Jan Raethjen, Hiroshi Shibasaki]
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Journal Title
Clin Neurophysiol
Volume: 132
Pages: 2608-2638
DOI
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Assessment of neurocognitive function in association with WHO grades in gliomas2021
Author(s)
Yamawaki R, Nankaku M, Umaba C, Ueda M, Liang N, Mineharu Y, Yamao Y, Ikeguchi R, Matsuda S, Miyamoto S, Arakawa Y.
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Journal Title
Clinical neurology and neurosurgery
Volume: 208
Pages: 106824
DOI
Peer Reviewed
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[Journal Article] Intraoperative hand strength as an indicator of consciousness during awake craniotomy: a prospective, observational study2021
Author(s)
Umaba C, Mineharu Y, Liang N, Mizota T, Yamawaki R, Ueda M, Yamao Y, Nankaku M, Miyamoto S, Matsuda S, Inadomi H, Arakawa Y.
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Journal Title
Scientific reports
Volume: 12
Pages: 216
DOI
Peer Reviewed
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[Presentation] Functional mapping for semantic processing in the ventral anterior temporal lobe by synonym judgment2021
Author(s)
Akihiro Shimotake, Katsuya Kobayashi, Kiyohide Usami, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Masao Matsuhashi, Takeharu Kunieda, Ryosuke Takahashi, Riki Matsumoto, Akio Ikeda
Organizer
第54回日本てんかん学会学術集会
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[Presentation] Functional mapping of semantic processing in the anterior temporal lobe2021
Author(s)
Akihiro Shimotake, Riki Matsumoto, Katsuya Kobayashi, Kiyohide Usami, Takayuki Kikuchi, Masao Matsuhashi, Kazumihchi Yoshida, Takeharu Kunieda, Susumu Miyamoto, Ryosuke Takahashi, Matthew Lambon-Ralph, Akio Ikeda
Organizer
第62回日本神経学会学術大会
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[Presentation] Semantic processing in the ventral anterior temporal lobe assessed by synonym judgement2021
Author(s)
Akihiro Shimotake, Riki Matsumoto, Katsuya Kobayashi, Kiyohide Usami, Takayuki Kikuchi, Masao Matsuhashi, Kazumihchi Yoshida, Takeharu Kunieda, Susumu Miyamoto, Ryosuke Takahashi, Matthew Lambon-Ralph, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] How to generate cortical tremor with rhythmicity?: Late repetitive event-related synchronization and desynchronization associated with giant SEPs2021
Author(s)
Haruo Yamanaka, Maya Tojima, Takefumi Hitomi, Katsuya Kobayashi, Masao Matsuhashi, Kazuki Oi, Hirofumi Takeyama, Kiyohide Usami, Akihiro Shimotake, Ryosuke Takahashi, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] LOW-DOSE PERAMPANEL IMPROVES REFRACTORY CORTICAL MYOCLONUS BY THE DISPERSED AND SUPPRESSED PAROXYSMAL DEPOLARIZATION SHIFTS IN THE SENSORIMOTOR CORTEX2021
Author(s)
Kazuki Oi, Shuichiro Neshige, Takefumi Hitomi, Katsuya Kobayashi, Maya Tojima, Masao Matsuhashi, Akihiro Shimotake, Daiki Fujii, Riki Matsumoto, Shuhei Kasama, Masutaro Kanda, Yoshiaki Wada, Hirofumi Maruyama, Ryosuke Takahashi, Akio Ikeda
Organizer
7th Asian-Oseanian Congress on Clinical Neurophysiology
Int'l Joint Research
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[Presentation] Cortical neuronal activities and their network dynamics during visual recognition2021
Author(s)
Kiyohide Usami, Riki Matsumoto, Anna Korzeniewska, Akihiro Shimotake, Masao Matsuhashi, Takuro Nakae, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Ryosuke Takahashi, Nathan Crone, Akio Ikeda
Organizer
第54回日本てんかん学会学術集会
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[Presentation] The dynamics of cortical interactions in category-specific visual recognition2021
Author(s)
Kiyohide Usami, Riki Matsumoto, Anna Korzeniewska, Akihiro Shimotake, Masao Matsuhashi, Takuro Nakae, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Ryosuke Takahashi, Nathan Crone, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] Living or non-living at the early-stage in mesoscale network dynamics during visual recognition2021
Author(s)
Kiyohide Usami, Riki Matsumoto, Anna Korzeniewska, Akihiro Shimotake, Masao Matsuhashi, Takuro Nakae, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Ryosuke Takahashi, Nathan Crone, Akio Ikeda
Organizer
第62回日本神経学会学術大会
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[Presentation] The dynamics of cortical interactions in category-specific visual recognition2021
Author(s)
Kiyohide Usami, Riki Matsumoto, Anna Korzeniewska, Akihiro Shimotake, Takuro Nakae, Masao Matsuhashi, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Ryosuke Takahashi, Nathan Crone, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] Slow and infraslow of scalp EEG is associated with transient neurological events in Moyamoya disease2021
Author(s)
Kozue Hayashi, Kiyohide Usami, Masaya Togo, Yukihiro Yamao, Akihiro Shimotake, Takeshi Funaki, Takefumi Hitomi, Takayuki Kikuchi, Masao Matsuhashi, Kazumichi Yoshida, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
Organizer
第62回日本神経学会学術大会
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[Presentation] Slow and infraslow of scalp EEG is associated with transient neurological events in Moyamoya disease2021
Author(s)
Kozue Hayashi, Kiyohide Usami, Masaya Togo, Yukihiro Yamao, Akihiro Shimotake, Takeshi Funaki, Takefumi Hitomi, Takayuki Kikuchi, Masao Matsuhashi, Kazumichi Yoshida, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] Reappraisal of abnormal EEG in migraine by wide-band scalp EEG: including differences from epilepsy2021
Author(s)
Kyoko Hosokawa, Kiyohide Usami, Yu Tatsuoka, Masayuki Honda, Takefumi Hitomi, Akihiro Shimotake, Masao Matsuhashi, Daisuke Danno, Takao Takeshima, Yoshihisa Tatsuoka, Ryosuke Takahashi, Akio Ikeda
Organizer
第54回日本てんかん学会学術集会
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[Presentation] Reappraisal of abnormal EEG in migraine by wide-band digital EEG2021
Author(s)
Kyoko Hosokawa, Kiyohide Usami, Yu Tatsuoka, Masayuki Honda, Takehumi Hitomi, Akihiro Shimotake, Masao Matsuhashi, Daisuke Danno, Takao Takeshima, Yoshihisa Tatsuoka, Ruosuke Takahashi, Akio Ikeda
Organizer
第62回日本神経学会学術大会
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[Presentation] Inter-ictal enhanced high frequency activities on the hypersynchronous pattern as a biomarker of the transition to epileptic seizures2021
Author(s)
Masahiro Gotoh, Katsuya Kobayashi, Shunsuke Kajikawa, Masao Matsuhashi, Kiyohide Usami, Akihiro Shimotake, Takefumi Hitomi, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Ryosuke Takahashi, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] Red slow in epilepsy surgery: Interictal co-occurrence of slow and high frequency activity2021
Author(s)
Masako Daifu-Kobayashi, Masao Matsuhashi, Morito Inouchi, Katsuya Kobayashi, Akihiro Shimotake, Takefumi Hitomi, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Riki Matsumoto, Ryosuke Takahashi, Akio Ikeda
Organizer
第62回日本神経学会学術大会
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[Presentation] Red slow in epilepsy surgery: Interictal co-occurrence of slow and high frequency activity in patients with epilepsy2021
Author(s)
Masako Daifu-Kobayashi, Masao Matsuhashi, Morito Inouchi, Katsuya Kobayashi, Akihiro Shimotake, Takefumi Hitomi, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Riki Matsumoto, Ryosuke Takahashi, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] Long term clinical course and volumetric change in patients with Anti-GAD Antibodies Associated Limbic Encephalitis2021
Author(s)
Masayuki Honda, Akihiro Shimotake, Katsuya Kobayashi, Mitsuhiro Sakamoto, Atushi Shima, Kozue Hayashi, Maya Tojima, Hirofumi Takeyama, Kiyohide Usami, Takefumi Hitomi, Riki Matsumoto, Ryosuke Takahashi, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] Hypometabolism of cerebral cortex in progressive myoclonus epilepsy2021
Author(s)
Maya Tojima, Atsushi Shima, Takefumi Hitomi, Tomohiko Murai, Hirofumi Takeyama, Katsuya Kobayashi, Kiyohide Usami, Akihiro Shimotake, Masao Matsuhashi, Nobukatsu Sawamoto, Ryosuke Takahashi, Akio Ikeda
Organizer
第62回日本神経学会学術大会
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[Presentation] Different hypometabolism of cerebral cortex among progressive myoclonus epilepsy2021
Author(s)
Maya Tojima, Atsushi Shima, Takefumi Hitomi, Tomohiko Murai, Hirofumi Takeyama, Katsuya Kobayashi, Kiyohide Usami, Akihiro Shimotake, Masao Matsuhashi, Nobukatsu Sawamoto, Ryosuke Takahashi, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] Anatomo-functional correlation of language areas: principal component analysis of mapping findings2021
Author(s)
Mayumi Otani, Riki Matsumoto, Akihiro Shimotake, Mitsuhiro Sakamoto, Takuro Nakae, Masao Matsuhashi, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Matthew A Lambon Ralph, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
Organizer
第62回日本神経学会学術大会
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[Presentation] Anatomo-functional correlation of language areas: principal component analysis of mapping findings2021
Author(s)
Mayumi Otani, Riki Matsumoto, Akihiro Shimotake, Mitsuhiro Sakamoto, Takuro Nakae, Masao Matsuhashi, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Matthew A Lambon Ralph, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] Direct, not network-mediated, electrical stimulation reduces excitability in the epileptic focus2021
Author(s)
Shunsuke Kajikawa, Katsuya Kobayashi, Riki Matsumoto, Tadashi Okada, Mayumi Otani, Masaya Togo, Kiyohide Usami, Akihiro Shimotake, Masao Matsuhashi, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Ryosuke Takahashi, Akio Ikeda
Organizer
第62回日本神経学術大会
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[Presentation] Direct, not network-mediated, electrical stimulation reduces excitability in the epileptic focus2021
Author(s)
Shunsuke Kajikawa, Katsuya Kobayashi, Riki Matsumoto, Tadashi Okada, Mayumi Otani, Masaya Togo, Kiyohide Usami, Akihiro Shimotake, Masao Matsuhashi, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Ryosuke Takahashi, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] Addition of MEG to specific consistency score improves outcome prediction after epilepsy surgery2021
Author(s)
Tadashi Okada, Maya Tojima, Yuhto Mitsuno, Yasunori Nagai, Akihiro Shimotake, Shuichiro Neshige, Kiyohide Usami, Masao Matsuhashi, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Riki Matsumoto, Takeharu Kunieda, Ryosuke Takahashi, Susumu Miyamoto, Akio Ikeda
Organizer
13th Asian & Oceanian Epilepsy Congress
Int'l Joint Research
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[Presentation] Addition of MEG to specific consistency score improves outcome prediction after epilepsy surgery2021
Author(s)
Tadashi Okada, Maya Tojima, Yuhto Mitsuno, Yasunori Nagai, Akihiro Shimotake, Shuichiro Neshige, Kiyohide Usami, Masao Matsuhashi, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Riki Matsumoto, Takeharu Kunieda, Takao Namiki, Ryosuke Takahashi, Susumu Miyamoto, Akio Ikeda
Organizer
第51回日本臨床神経生理学会学術大会
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[Presentation] No or little progression of EEG abnormality in benign adult familial myoclonus epilepsy (BAFME)2021
Author(s)
Takefumi Hitomi, Maya Tojima, Kazuki Oi, Shamima Sultana, Masayuki Honda, Hirofumi Takeyama, Katsuya Kobayashi, Akihiro Shimotake, Kiyohide Usami, Masao Matsuhashi, Ryosuke Takahashi, Akio Ikeda
Organizer
第62回日本神経学会学術大会
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[Presentation] 過運動発作の難治性部分てんかんの術前評価における硬膜外電極の特別な有用性の検討2021
Author(s)
永井 俊行, 宇佐美 清英, 後藤 昌広, 尾谷 真弓, 光野 優人, 山田 大輔, 山尾 幸広, 吉田 和道, 菊池 隆幸, 松橋 眞生, 池田 昭夫
Organizer
第51回日本臨床神経生理学会学術大会
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[Presentation] 発作時頭皮脳波開始前にDC電位を認めた粗大病変の難治左側頭葉てんかんの一例2021
Author(s)
永井 俊行, 下竹 昭寛, 後藤 昌広, 戸島 麻耶, 梶川 駿介, 山尾 幸広, 宇佐美 清英, 菊池 隆幸, 松橋 眞生, 髙橋 良輔, 池田 昭夫
Organizer
第17回日本てんかん学会近畿地方会
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[Presentation] てんかん外科治療適応の評価におけるMEGの意義の後方視的検討2021
Author(s)
岡田 直, 戸島 麻耶, 光野 優人, 永井 靖識, 下竹 昭寛, 音成 秀一郎, 宇佐美 清英, 松橋 眞生, 山尾 幸広, 菊池 隆幸, 吉田 和道, 松本 理器, 國枝 武治, 髙橋 良輔, 宮本 享, 池田 昭夫
Organizer
第62回日本神経学会学術大会
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[Presentation] Specific consistency scoreにMEGによる評価を追加することでてんかん手術後の転帰予測を改善する2021
Author(s)
岡田 直, 戸島 麻耶, 光野 優人, 永井 靖識, 下竹 昭寛, 音成 秀一郎, 宇佐美 清英, 松橋 眞生, 山尾 幸広, 菊池 隆幸, 吉田 和道, 松本 理器, 國枝 武治, 髙橋 良輔, 宮本 享, 池田 昭夫
Organizer
第54回日本てんかん学会学術集会
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[Presentation] 時定数2秒の頭皮上脳波でinfraslowとcyclic seizure patternを記録できた1例の臨床的意義2021
Author(s)
梶川 駿介, 人見 健文, 北野 和樹, 十河 正弥, 三村 直哉, 宇佐美 清英, 小林 勝哉, 下竹 昭寛, 松橋 眞生, 髙橋 良輔, 池田 昭夫
Organizer
第35回日本神経救急学会学術集会
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[Presentation] 時定数2秒の頭皮上脳波でcyclic seizure patternに伴うinfraslow oscillationを呈した1例2021
Author(s)
梶川 駿介, 人見 健文, 北野 和樹, 十河 正弥, 三村 直哉, 宇佐美 清英, 小林 勝哉, 下竹 昭寛, 松橋 眞生, 髙橋 良輔, 池田 昭夫
Organizer
第51回日本臨床神経生理学会学術大会
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[Presentation] てんかん外科治療適応を客観的・効率的に評価するスコアシステム導入: Specific Consistency Scoreの検討2021
Author(s)
戸島 麻耶, 下竹 昭寛, 音成 秀一郎, 岡田 直, 小林 勝哉, 宇佐美 清英, 松橋 眞生, 吉田 健司, 伏見 育崇, 山尾 幸広, 菊池 隆幸, 吉田 和道, 行木 孝夫, 松本 理器, 國枝 武治, 宮本 享, 池田 昭夫
Organizer
第54回日本てんかん学会学術集会
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[Presentation] てんかん外科治療適応の効率的評価のためのスコアリングシステム: Specific Consistency Scoreの重み付けの検討2021
Author(s)
戸島 麻耶, 下竹 昭寛, 音成 秀一郎, 岡田 直, 本多 正幸, 武山 博文, 小林 勝哉, 宇佐美 清英, 人見 健文, 松橋 眞生, 吉田 健司, 伏見 育崇, 岡田 知久, 山尾 幸広, 菊池 隆幸, 吉田 和道, 行木 孝夫, 松本 理器, 國枝 武治, 髙橋 良輔, 宮本 享, 池田 昭夫
Organizer
第44回日本てんかん外科学会
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[Presentation] 難治性てんかんにおいて細胞外K濃度の変動状態が発作発現に関与する可能性2021
Author(s)
後藤 昌広, 梶川 駿介, 宇佐美 清英, 下竹 昭寛, 小林 勝哉, 人見 健文, 山尾 幸広, 菊池 隆幸, 吉田 和道, 宮本 享, 松橋 眞生, 大野 行弘, 髙橋 良輔, 池田 昭夫
Organizer
第16回日本てんかん学会近畿地方会
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[Presentation] Hypersynchronous patternを呈した側頭葉てんかんの発作移行への分岐点は?2021
Author(s)
後藤 昌広, 梶川 駿介, 宇佐美 清英, 下竹 昭寛, 小林 勝哉, 人見 健文, 山尾 幸広, 菊池 隆幸, 吉田 和道, 松橋 眞生, 髙橋 良輔, 池田 昭夫
Organizer
第62回日本神経学会学術大会
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[Presentation] Hypersynchronous patternに重畳する高周波活動の解析: 発作の予測・早期検出マーカーとしての可能性2021
Author(s)
後藤 昌広, 梶川 駿介, 宇佐美 清英, 下竹 昭寛, 小林 勝哉, 人見 健文, 山尾 幸広, 菊池 隆幸, 吉田 和道, 松橋 眞生, 髙橋 良輔, 池田 昭夫
Organizer
第54回日本てんかん学会学術集会
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[Presentation] 過運動発作の硬膜外電極脳波記録における発作時高周波活動の進展様式解析はてんかん焦点側方性同定に有用となりうる2021
Author(s)
後藤 昌広, 小林 勝哉, 尾谷 真弓, 松橋 眞生, 宇佐美 清英, 下竹 昭寛, 山田 大輔, 光野 優人, 山尾 幸広, 菊池 隆幸, 吉田 和道, 池田 昭夫
Organizer
第51回日本臨床神経生理学会学術大会
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[Presentation] 変性疾患による認知症の脳波所見の相違: 視察と自動判読による検討2021
Author(s)
佐藤 啓, 人見 健文, 松橋 眞生, 小林 勝哉, 下竹 昭寛, 葛谷 聡, 木下 彩栄, 松本 理器, 武地 一, 杉 剛直, 西田 茂人, 高橋 良輔, 池田 昭夫
Organizer
第51回日本臨床神経生理学会学術大会
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[Presentation] 広域周波数帯域脳波 (wide-band EEG) 解析を用いた片頭痛における低周波帯域を中心とした脳波所見の再検討2021
Author(s)
細川 恭子, 宇佐美 清英, 立岡 悠, 本多 正幸, 人見 健文, 下竹 昭寛, 松橋 眞生, 團野 大介, 竹島 多賀夫, 立岡 良久, 髙橋 良輔, 池田 昭夫
Organizer
第51回日本臨床神経生理学会学術大会
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[Presentation] BAFMEのcortical tremorの発生機構:巨大SEPに後続反復する広周波数帯域の同期と脱同期2021
Author(s)
山中 治郎, 戸島 麻耶, 小林 勝哉, 人見 健文, 松橋 眞生, 大井 和起, 武山 博文, 宇佐美 清英, 下竹 昭寛, 髙橋 良輔, 池田 昭夫
Organizer
第62回日本神経学会学術大会
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[Presentation] Giant SEPにおける短-中潜時成分は発作性脱分極シフトの指標となりうるか2021
Author(s)
石橋 はるか, 戸島 麻耶, 人見 健文, 音成 秀一郎, 小林 勝哉, 本多 正幸, 武山 博文, 宇佐美 清英, 下竹 昭寛, 松橋 眞生, 丸山 博文, 髙橋 良輔, 池田 昭夫
Organizer
第62回日本神経学会学術大会
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[Presentation] 巨大SEPの短-中潜時成分は突発性脱分極偏位と後続する抑制成分を反映しうる2021
Author(s)
石橋 はるか, 戸島 麻耶, 人見 健文, 小林 勝哉, 山中 治郎, 松橋 眞生, 音成 秀一郎, 宇佐美 清英, 下竹 昭寛, 本多 正幸, 丸山 博文, 高橋 良輔, 池田 昭夫
Organizer
第51回日本臨床神経生理学会学術大会
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[Presentation] くすぶり型の抗GAD抗体陽性辺縁系脳炎患者群の長期経過:臨床的特徴と海馬・扁桃体容積の検討2021
Author(s)
本多 正幸, 下竹 昭寛, 小林 勝哉, 坂本 光弘, 島 淳, 林 梢, 戸島 麻耶, 武山 博文, 宇佐美 清英, 人見 健文, 松本 理器, 髙橋 良輔, 池田 昭夫
Organizer
第62回日本神経学会学術大会
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