2011 Fiscal Year Final Research Report
Super-resolution sensing using nanolasers
| Project/Area Number |
21246014
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Applied optics/Quantum optical engineering
|
|---|
| Research Institution | Yokohama National University |
|---|
Principal Investigator |
BABA Toshihiko 横浜国立大学, 工学研究院, 教授 (50202271)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | ナノレーザ / フォトニック結晶 / バイオフォトニクス / バイオセンシング |
|---|
| Research Abstract |
We developed high-sensitivity bio-sensor based on photonic crystal nanolasers with a nano-slot structure. In a test experiment against BSA protein with a low attachment force, a very low detection limit of 255 fM was achieved, suggesting an excellent sensitivity. In a more practical experiment against SA protein, an ultralow concentration of 60 zM was detected without contaminants and<1 aM even with 1 trillion higher concentration BSA as contaminants. These results satisfy the requirements from medical diagnoses for detecting low-concentration bio-markers in human blood.
|
Research Products
(33 results)
