2011 Fiscal Year Final Research Report
Mechanism of activation and inactivation of cell viability by generation and transport control of biological reactive plasma flow
| Project/Area Number |
21246032
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fluid engineering
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| Research Institution | Tohoku University |
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Principal Investigator |
SATO Takehiko 東北大学, 流体科学研究所, 教授 (10302225)
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| Co-Investigator(Kenkyū-buntansha) |
OHARA Taku 東北大学, 流体科学研究所, 教授 (40211833)
JOHKURA Kohei 信州大学, 医学部, 准教授 (30303473)
MIYAHARA Takashi 静岡大学, 工学部, 教授 (70239432)
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| Project Period (FY) |
2009 – 2011
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| Keywords | バイオ流体力学 |
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| Research Abstract |
The chemical species of the biological reactive plasma flow was mainly transported by the generation of the expanding high temperature gas flow on the water surface and induced water flow due to the gas flow. Hydrogen peroxide among the stable chemical species generated by the plasma flow was identified as an important inactivation factor of the HeLa cell viability by the morphological variation process, the effect of catalase, the gene expression analysis, and so on. The energy transport in the cell membrane was affected by the transport directions and molecular types.
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