2012 Fiscal Year Final Research Report
Effects of Exercise on Intensities of Expressions of Receptors onNK Cell Subsets
| Project/Area Number |
21300257
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Meiji University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2012
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| Keywords | NK 細胞 / 運動 / レセプター / CD56dim / CD56bright |
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| Research Abstract |
In these studies，we examined the impacts of acute and chronic exercise on the functional receptors on NK cell in human. The results indicated that both induced changes in the expressions of molecules. These changes were mainly found in CD56dim NK cell. Some of changes in adhesion molecules seemed to contribute to cell mobilization. However, changes in activating/inhibitory receptors did not directly relate to the cell cytotoxicity. We also indicated the possibility that acute exercise stimulated cell turnover in the liver in mice.
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