2011 Fiscal Year Final Research Report
Studies on the molecular mechanisms of induction and suppression of RNA silencing in plants
| Project/Area Number |
21380034
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Plant pathology
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| Research Institution | National Institute of Agrobiological Sciences |
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Principal Investigator |
MESHI Tetsuo 独立行政法人農業生物資源研究所, 植物科学研究領域, 領域長 (40157813)
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| Co-Investigator(Kenkyū-buntansha) |
ISHIKAWA Masayuki 独立行政法人農業生物資源研究所, 植物科学研究領域・植物-微生物間相互作用研究ユニット, ユニット長 (70192482)
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| Project Period (FY) |
2009 – 2011
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| Keywords | RNAサイレンシング / 植物 / ウイルス |
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| Research Abstract |
RNA silencing is one of major antiviral responses in plants. In RNA silencing, RNA-induced silencing complexes(RISCs) recognize target mRNAs to inhibit the expression of corresponding proteins. Here, we found that AGO1 protein binds double-stranded small interfering RNAs(siRNAs) with the help of a molecular chaperone HSP90 and its co-chaperone CYP40, and then, one of the siRNA strands is removed to form an active RISC.
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Research Products
(8 results)
