Development and application ofnovel myelin imaging by magnetic susceptibility-weighted imaging using a high-field MR equipment

2012 Fiscal Year Final Research Report

• Project/Area Number: 21390344
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: Osaka City University
• Principal Investigator: MIKI Yukio 大阪市立大学, 大学院・医学研究科, 教授 (80303824)
• Co-Investigator(Kenkyū-buntansha): KANAGAKI Mitsunori 京都大学, 大学院・医学研究科, 助教 (50378676) ; YAMAMOTO Akira 京都大学, 大学院・医学研究科, 助教 (60525567)
• Project Period (FY): 2009 – 2012
• Keywords: 核磁気共鳴画像 / MRI / 髄鞘イメージング

Research Abstract

We have demonstrated that susceptibility-weighted imaging at 3T can constantly delineate the entire length of the optic radiation. We also obtained susceptibility-weighted images before and after temporal lobectomy for patients with temporal lobe epilepsy

Research Products

• [Journal Article] Post-embolisationsusceptibility changes in giant meningiomas: multiparametric histogramanalysis using non-contrast-enhanced susceptibility-weighted PRESTO, diffusion-weighted and perfusion-weighted imaging. (2013)
  • Author(s): Nishiguchi T, Iwakiri T, Hayasaki K, Ohsawa M, Yoneda T, Mitsuhashi Y, NishioA, Dousset V, Miki Y
  • Journal Title: Eur Radiol Volume: 23(2) Pages: 551-61
  • DOI: doi:10.1007/s00330-012-2618-8
  • Peer Reviewed
• [Journal Article] Imaging appearance of petrous apex dermoid cysts containing little or no fat. (2013)
  • Author(s): Ageshio N, Shimono T, Goto T, Ohata K,Ohsawa M, Wakasa K, Miki Y
  • Journal Title: Jpn J Radiol Volume: 31(2) Pages: 133-7
  • DOI: doi:10.1007/s11604-012-0150-z
  • Peer Reviewed
• [Journal Article] Diagnosis of moyamoya disease using 3-T MRI and MRA: value of cisternal moyamoya vessels. (2012)
  • Author(s): Sawada T, Yamamoto A, Miki Y, Kikuta KI, Okada T, Kanagaki M, Kasahara S, Miyamoto S, Takahashi JC, Fukuyama H, Togashi K
  • Journal Title: Neuroradiology Volume: 54(10) Pages: 1089-97
  • DOI: doi:10.1007/s00234-012-1020-1
  • Peer Reviewed
• [Journal Article] Three-dimensional double-echo steady-state (3D-DESS) magnetic resonance imaging of the knee: establishment of flip angles for evaluation of cartilage at 1.5 T and 3.0 T. (2012)
  • Author(s): Moriya S, Miki Y, Matsuno Y, Okada M
  • Journal Title: Acta Radiol Volume: 53(7) Pages: 790-4
  • DOI: doi:10.1258/ar.2012.110532
  • Peer Reviewed
• [Journal Article] Development of a highly efficient implanted thermal ablation device: in vivo experiment in rat liver (2012)
  • Author(s): Matsui H, Hamuro M, Nakamura K, Kayahara H, Murano K, Kotsuka Y, Miki Y
  • Journal Title: Br J Radiol Volume: 85(1017) Pages: e734-9
  • DOI: doi:10.1259/bjr/52571099
  • Peer Reviewed
• [Journal Article] Fat-suppressed MR images of both hands obtained using CHESS can be improved by rice pads (2012)
  • Author(s): Moriya S, Miki Y, Kamishima T, Kanagaki M, Yokobayashi T, Ishikawa M
  • Journal Title: Eur J Radiol Volume: 81(9) Pages: 2318-22
  • DOI: doi:10.1016/j.ejrad.2011.06.021
  • Peer Reviewed
• [Journal Article] Experimental venous thrombi: MRI characteristics with histopathological correlation (2012)
  • Author(s): Ichiki M, Sakai Y, Nango M, Nakamura K, Matsui H, Cho H, Kitayama T, Sahara T, Otani N, Inoue Y, Miki Y
  • Journal Title: Br J Radiol Volume: 85(1012) Pages: 331-8
  • Peer Reviewed
• [Journal Article] "Hot cross bun" sign in multiple system atrophy with predominant cerebellar ataxia: A comparison between proton density-weighted imaging and T2-weighted imaging. (2012)
  • Author(s): Kasahara S, Miki Y, Kanagaki M, Kondo T, Yamamoto A, Morimoto E, Okada T, Ito H, Takahashi R, Togashi K
  • Journal Title: Eur J Radiol Volume: 81(10) Pages: 2848-52
  • DOI: doi:10.1016/j.ejrad.2011.12.012
  • Peer Reviewed
• [Journal Article] Successful Balloon-Occluded RetrogradeTransvenous Obliteration for Gastric Varix Mainly Draining into the Pericardiophrenic Vein (2012)
  • Author(s): Kageyama K, Nishida N, Matsui H, Yamamoto A, Nakamura K, Miki Y
  • Journal Title: Cardiovasc Intervent Radiol Volume: 35(1) Pages: 180-3
  • DOI: doi:10.1007/s00270-011-0233-8
  • Peer Reviewed
• [Journal Article] Fat-suppressed MR images of both handsobtained using CHESS can be improved byrice pads (2012)
  • Author(s): Moriya S, Miki Y, Kamishima T, KanagakiM, Yokobayashi T, Ishikawa M
  • Journal Title: Eur J Radiol Volume: 81(9) Pages: 2318-2322
  • DOI: doi:10.1016/j.ejrad.2011.06.021
  • Peer Reviewed
• [Journal Article] Evaluation of cartilagesurface injuries using 3D-double echo steady state (3D-DESS): effect of changing flip angle from 40° to 90°. (2011)
  • Author(s): Moriya S, Miki Y, Kanagaki M, YamamotoA, Okudaira S, Nakamura S, YokobayashiT, Ishikawa M
  • Journal Title: Acta Radiol Volume: 52(10) Pages: 1138-42
  • DOI: doi:10.1258/ar.2011.110275
  • Peer Reviewed
• [Journal Article] Optimization of the number of selectable channels for spine phased array coils for transverse imaging. (2011)
  • Author(s): Moriya S, Miki Y, Yokobayashi T, Yamamoto A, Kanagaki M, Komori Y, Fujimoto K, Ishikawa M
  • Journal Title: Jpn J Radiol Volume: 29(3) Pages: 166-70
  • DOI: doi:10.1007/s11604-010-0532-z
  • Peer Reviewed
• [Journal Article] Differentiating Benign Notochordal Cell Tumors From Chordomas:Radiographic Features on MRI, CT, and Tomography (2011)
  • Author(s): Nishiguchi T, Mochizuki K, Ohsawa M, Inoue T, Kageyama K, Suzuki A, Takami T,Miki Y
  • Journal Title: AJR Am J Roentgenol Volume: 196(3) Pages: 644-50
  • DOI: doi:10.2214/AJR.10.4460
  • Peer Reviewed
• [Journal Article] Hyperintense dentate nucleus on unenhanced T1-weighted MR images is associated with a history of brain irradiation (2011)
  • Author(s): Kasahara S, Miki Y, Kanagaki M, Yamamoto A, Mori N, Sawada T, Taoka T, Okada T,Togashi K
  • Journal Title: Radiology Volume: 258(1) Pages: 222-8
  • DOI: doi:10.1148/radiol.10100508
  • Peer Reviewed
• [Journal Article] Computed tomography and magnetic resonance imaging appearance of prolactinoma with spheroid-type amyloid deposition (2011)
  • Author(s): Kitamura K, Nakayama T, Ohata K, WakasaK, Miki Y
  • Journal Title: J Comput Assist Tomogr Volume: 35(2) Pages: 313-5
  • DOI: doi:10.1097/RCT.0b013e31820d7bdf
  • Peer Reviewed
• [Journal Article] Rice Pads Reduce Geometric Distortion of Echo-planar Diffusion-weighted Images of the Cervical Spinal Cord (2011)
  • Author(s): Moriya S, Miki Y, Yokobayashi T, Kanagaki M, Komori Y, Fujimoto K, Ishikawa M
  • Journal Title: Magn Reson Med Sci Volume: 10(1) Pages: 65-9
  • URL: https://www.jstage.jst.go.jp/article/mrms/10/1/10_1_65/_pdf
  • Peer Reviewed
• [Journal Article] Analysis of cyclosporin A-induced reversible cortical blindness by diffusion-weighted magnetic resonance imaging techniques (2010)
  • Author(s): Manabe S, Kashii S, Miki Y, Honda Y
  • Journal Title: Jpn J Ophthalmol Volume: 54(3) Pages: 248-50
  • DOI: doi:10.1007/s10384-009-0792-2
  • Peer Reviewed
• [Journal Article] Axonal damage in acute cerebral infarction showing ADC reduction (2010)
  • Author(s): Ueno M, Onodera M, Naya T, Toyama Y, Hosomi N, Huang CL, Nishiyama Y, Kusaka T, Miki Y, Kohno M, Tomimoto H, Sakamoto H
  • Journal Title: J Neurol Volume: 257(9) Pages: 1559-61
  • DOI: doi:10.1007/s00415-010-5537-0
  • Peer Reviewed
• [Journal Article] Signal changes in the brain on susceptibility-weighted imaging under reduced cerebral blood flow: a preliminary study. (2010)
  • Author(s): Fushimi Y, Miki Y, Mori N, Okada T, Urayama S, Fukuyama H, Togashi K
  • Journal Title: J Neuroimaging Volume: 20(3) Pages: 255-9
  • DOI: doi:10.1111/j.1552-6569.2008.00348.x
  • Peer Reviewed
• [Journal Article] Improved CHESS imaging with the use of rice pads: Investigation in the neck, shoulder, and elbow. (2010)
  • Author(s): Moriya S, Miki Y, Yokobayashi T, Yamamoto A, Kanagaki M, Komori Y, Fujimoto K, Ishikawa M
  • Journal Title: J Magn Reson Imaging Volume: 31(6) Pages: 1504-7
  • DOI: doi:10.1002/jmri.22189
  • Peer Reviewed
• [Journal Article] Rice and perfluorocarbon liquid pads: comparison of fat suppression effects (2010)
  • Author(s): Moriya S, Miki Y, Yokobayashi T, Yamamoto A, Kanagaki M, Komori Y, Ishikawa M
  • Journal Title: Acta Radiol Volume: 51(5) Pages: 534-8
  • DOI: doi:10.3109/02841851003645744
  • Peer Reviewed
• [Journal Article] Rice pads: Novel devices for homogeneous fat suppression in the knee (2010)
  • Author(s): Moriya S, Miki Y, Yokobayashi T, Kanagaki M, Komori Y, Ishikawa M
  • Journal Title: Acta Radiol Volume: 51(2) Pages: 175-8
  • DOI: doi:10.3109/02841850903321633
  • Peer Reviewed
• [Journal Article] Normal pituitary stalk: high-resolution MR imaging at 3T (2010)
  • Author(s): Satogami N, Miki Y, Koyama T, Kataoka M,Togashi K
  • Journal Title: AJNR Am J Neuroradiol Volume: 31(2) Pages: 355-9
  • DOI: doi:10.3174/ajnr.A1836
  • Peer Reviewed
• [Journal Article] Chest wall temperature during radiofrequency ablation in a normal rabbit lung model (2010)
  • Author(s): Okuma T, Matsuoka T, Yamamoto A, Hamamoto S, Kageyama K, Nakamura K, Miki Y
  • Journal Title: Jpn J Radiol Volume: 28(1) Pages: 48-52
  • DOI: doi:10.1007/s11604-009-0384-6
  • Peer Reviewed
• [Journal Article] Quantitative imaging of spontaneous neuromagnetic activity for assessing cerebral ischemia using sLORETA-qm (2010)
  • Author(s): Sakamoto S, Tanaka H, Tsuyuguchi N, Terakawa Y, Ohata K, Inoue Y, Miki Y, Takahashi Y, Nitta K, Sawa H, Satone A,Ide W, Hashimoto I, Kamada H
  • Journal Title: Neuroimage Volume: 49(1) Pages: 488-97
  • DOI: doi:10.1016/j.neuroimage.2009.07.039
  • Peer Reviewed
• [Journal Article] Guideline touse gadolinium-based contrast agents at Kyoto University Hospital (2009)
  • Author(s): Miki Y, Isoda H, Togashi K
  • Journal Title: J Magn ResonImaging Volume: 30(6) Pages: 1364-5
  • DOI: doi:10.1002/jmri.21978
  • Peer Reviewed
• [Journal Article] Leukoencephalopathy with cognitive impairment following tocilizumab for the treatment of rheumatoid arthritis (RA) (2009)
  • Author(s): Kobayashi K, Okamo Y, Inoue H, Usui T,Ihara M, Kawamata J, Miki Y, Mimori T,Tomimoto H, Takahashi R
  • Journal Title: Internal Medicine Volume: 48(15) Pages: 1307-1309
  • URL: https://www.jstage.jst.go.jp/article/internalmedicine/48/15/48_15_1307/_pdf
  • Peer Reviewed
• [Journal Article] Spin-echo T1-weighted imaging of the brain with interleaved acquisition and presaturation pulse at 3T: A feasibility study before clinical use. (2009)
  • Author(s): Kasahara S, Miki Y, Fushimi Y, UrayamaS-I, Mori N, Kanagaki M, Maeda C, Sawamoto N, Fukuyama H, Togashi K
  • Journal Title: Acad Radiol Volume: 16(7) Pages: 852-7
  • DOI: doi:10.1016/j.acra.2008.12.026
  • Peer Reviewed
• [Journal Article] Susceptibility-weighted Imaging at 3T Delineates the Optic Radiation (2009)
  • Author(s): Mori N, Miki Y, Kasahara S, Maeda C, Kanagaki M, Urayama S, Sawamoto N, Fukuyama H, Togashi K
  • Journal Title: Invest Radiol Invest Radiol Volume: 44(3) Pages: 140-5
  • DOI: doi:10.1097/RLI.0b013e318193ff25
  • Peer Reviewed
• [Journal Article] Visualization of the lenticulostriate artery with Flow-Sensitive Black-Blood acquisition in comparison with Time-of-Flight MR angiography (2009)
  • Author(s): Gotoh K, Okada T, Miki Y, Ikedo M, Ninomiya A, Kamae T, Togashi K
  • Journal Title: J Magn Reson Imaging Volume: 29(1) Pages: 65-9
  • DOI: doi:10.1002/jmri.21626
  • Peer Reviewed
• [Journal Article] Tissue contrast imaging using PADREimproves delineation of micro-calcifications
  • Author(s): Maeda H, Yoneda T, Sakamoto S, ShimonoT, Suzuki Y, Katayama Y, Yamada E, Miki Y
  • Journal Title: a phantom study
• [Journal Article] Meyer's loop depicted on magnitude images of susceptibility-weighted imaging: Preand postoperative perimetric validation in patients with temporal lobe epilepsy
  • Author(s): Mori S, Miki Y, Mikuni N, Matsumoto R,Kanagaki M, Yamamoto A, Kasahara S
  • Journal Title: Radiology Volume: (submitted)
  • Peer Reviewed
• [Presentation] 炎症性脱髄疾患 (2013)
  • Author(s): 三木幸雄
  • Organizer: 第42回日本神経放射線学会
  • Place of Presentation: (北九州国際会議場)福岡
  • Year and Date: 2013-02-16
• [Presentation] Acute Demyelination (2012)
  • Author(s): Miki Y
  • Organizer: 20th Scientific Meeting of International Society for Magnetic Resonance in Medicine (ISMRM)
  • Place of Presentation: (Melbourne Convention & Exhibition Centre) Melbourne, Victoria, Australia
  • Year and Date: 20120505-11
• [Presentation] MRI 評価 (2012)
  • Author(s): 三木幸雄
  • Organizer: 第24回日本神経免疫学会学術集会イブニングセミナー
  • Place of Presentation: (軽井沢プリンスホテルウエスト)軽井沢
  • Year and Date: 2012-09-20
• [Presentation] 脳の高磁場(3T)MRI について:1.5T との比較を含めて (2012)
  • Author(s): 三木幸雄
  • Organizer: 第63回日本脳神経外科学会近畿支部学術集会
  • Place of Presentation: (千里ライフサイエンスセンター)大阪
  • Year and Date: 2012-04-07
• [Presentation] 下垂体・傍鞍部の画像診断 (2012)
  • Author(s): 三木幸雄
  • Organizer: 第41回日本神経放射線学会
  • Place of Presentation: (北九州国際会議場)福岡
  • Year and Date: 2012-02-02
• [Presentation] 磁化率強調画像によるMeyer's loop の抽出:側頭葉てんかん手術前後の所見および視野検査との対照 (2011)
  • Author(s): 森暢幸、三木幸雄、三國信啓、松本理器、金柿光憲、山本憲、岡田知久、野間恵之、富樫かおり
  • Organizer: 第70回 日本医学放射線学会総会
  • Place of Presentation: Web
  • Year and Date: 20110509-20
• [Presentation] Meyer's loop delineated on magnitude images of susceptibility-weighted imaging: pre- and postoperative perimetric correlation in patients withrefractory temporal lobe epilepsy (2011)
  • Author(s): Mori N, Miki Y, Mikuni N, Matsumoto R,Kasahara S, Morimoto E, Kanagaki M, Yamamoto A, Okada T, Noma S, Togashi K
  • Organizer: International Society for Magnetic Resonance in Medicine (ISMRM)
  • Place of Presentation: (Palaisdes congres de Montreal)Montreal, Quebec, Canada
  • Year and Date: 20110507-13
• [Presentation] MRI of Pathological Aging Brain (2011)
  • Author(s): Miki Y
  • Organizer: 19th Scientific Meeting of International Society for Magnetic Resonance in Medicine (ISMRM)
  • Place of Presentation: (Palais des congres de Montreal)Montreal, Canada
  • Year and Date: 2011-05-12
• [Presentation] SWI 信号強度画像によるMeyer's loop 描出:側頭葉てんかん手術前後での視野検査との統計学的検討. (2010)
  • Author(s): 森暢幸、三木幸雄、三國信啓、松本理器、金柿光憲、山本憲、岡田知久、野間恵之、富樫かおり
  • Organizer: 第72回 日本医学放射線学会総会
  • Place of Presentation: (パシフィコ横浜)横浜
  • Year and Date: 20100410-13
• [Presentation] Meyer's loop depicted on magnitude images of susceptibility weighted imaging: Preand postoperative perimetric validation in patients with temporal lobe epilepsy (2010)
  • Author(s): Mori N, Miki Y, Mikuni N, Matsumoto R, Kanagaki M, Yamamoto A, Kasahara S, Sawada T, Togashi K
  • Organizer: European Congress of Radiology
  • Place of Presentation: (Austria Center Vienna)Vienna, Austria
  • Year and Date: 20100304-08
• [Presentation] Imaging of White Matter Diseases (2010)
  • Author(s): Miki Y
  • Organizer: XIX Symposium Neuroradiologicum (The 19th World Congress of Neuroradiology)
  • Place of Presentation: (Palazzo della cultura e dei congressi)Bologna, Italy
  • Year and Date: 2010-10-06
• [Presentation] Demyelinating disorders (2009)
  • Author(s): Miki Y
  • Organizer: Advanced imaging multimodality seminars(AIMS)
  • Place of Presentation: (Sapia tower)Tokyo
  • Year and Date: 2009-07-25
• [Book] 放射線医学脳画像診断 (2012)
  • Author(s): 三木幸雄
  • Total Pages: 130
  • Publisher: 金芳堂