2011 Fiscal Year Final Research Report
A study of male infertility as genome diseases-Recombination of genome DNA and sperm typing-
| Project/Area Number |
21390438
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Kanazawa University |
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Principal Investigator |
KOH Eitetsu 金沢大学, 医学系, 准教授 (90283134)
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| Co-Investigator(Kenkyū-buntansha) |
NAMIKI Mikio 金沢大学, 医学系, 教授 (70155985)
MAEDA Yuji 金沢大学, 附属病院, 助教 (20377394)
KANAYA Jiro 金沢大学, 附属病院, 助教 (80432128)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 精子 / ヒトゲノム / ハプロタイプ,再組換え / 繰り返し配列 / Y染色体 / 減数 |
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| Research Abstract |
We evaluated an analysis of the single sperm DNA in the meiotic system regarding process of spermatogenesis. According to the sequence of the haplotype, much repeat sequence existed in Y chromosome. We confirmed much these repeat sequence involved a human endogenous retrovirus(HERV). The phylogenetic analysis showed a Y-specific palindromic structural existed since old world monkey. This study proved the presence of palindrome 1, 2 since an early evolutionary stage was associated with spermatogenesis
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Research Products
(7 results)
