2011 Fiscal Year Final Research Report
Investigation into the pathology of ocular ischemic disorders by controlling the the blood cell-endothelial cell interactions and hypoxia imaging
| Project/Area Number |
21390466
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Ophthalmology
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
YOSHIMURA Nagahisa 京都大学, 大学院・医学研究科, 教授 (70211662)
TSUJIKAWA Akitaka 京都大学, 大学院・医学研究科, 講師 (40402846)
NONAKA Atsushi 京都大学, 大学院・医学研究科, 助教 (40532601)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | 眼虚血性疾患 / 網膜循環 / 網膜静脈閉塞症 / 黄斑浮腫 / IS/OSライン / 漿液性網膜剥離 / ミュラー細胞円錐 / 黄斑部局所網膜電図 |
|---|
| Research Abstract |
We investigated the pathology of retinal vein occlusion(RVO) that is a representative disease of retinal circulatory disturbances, one of ocular ischemic disorders. The followings were elucidated : 1) in eyes with macular edema associated with RVO, when the junction line between inner and outer segments of the photoreceptors was detected beneath the fovea, they would be expected to have good vision after resolution of the macular edema, 2) the foveal architecture, especially that of the Muller cell cone, plays an important role in the formation of serous retinal detachment associated with RVO, and 3) focal macular electroretinography is useful as a functional examination within the macular area affected by RVO, etc.
|
