2011 Fiscal Year Final Research Report
New development of bFGF/ poly-phosphate adsorbed artificial bone
| Project/Area Number |
21390517
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
AKAGAWA Yasumasa 広島大学, 大学院・医歯薬学総合研究科, 教授 (00127599)
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| Co-Investigator(Kenkyū-buntansha) |
KUBO Takayasu 広島大学, 病院, 講師 (60240876)
KORETAKE Katsuniri 広島大学, 大学院・医歯薬学総合研究科, 助教 (50346508)
DOI Kazuya 広島大学, 大学院・医歯薬学総合研究科, 助教 (80444686)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 骨再生 / 連通多孔性アパタイト / ポリリン酸 |
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| Research Abstract |
The purpose of this study was to evaluate the bone formation ability of newly developed composite of bFGF and poly(P) adsorbed artificial bone. The results of this study indicate that co-application of bFGF and poly(P) may provide enhanced cell proliferation and mineralization in vitro and bone formation in vivo. It is anticipated that combined application of bFGF and poly(P) adsorbed artificial bone can provide a novel method for guided bone regeneration in clinical use
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