2011 Fiscal Year Final Research Report
The construction and maintenance of titanium-tissue interface by the enhancement of both t issue response and titanium functionalization
| Project/Area Number |
21390520
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Kyushu University |
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Principal Investigator |
KIYOSHI Koyano 九州大学, 大学院・歯学研究院, 教授 (50195872)
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| Co-Investigator(Kenkyū-buntansha) |
AYUKAWA Yasunori 九州大学, 大学病院, 講師 (50304697)
OGINO Yoichiro 九州大学, 大学病院, 助教 (50380431)
ATSUTA Ikiru 九州大学, 大学院・歯学研究院, 助教 (30423487)
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| Co-Investigator(Renkei-kenkyūsha) |
ISHIKAWA Kunio 九州大学, 大学院・歯学研究院, 教授 (90202952)
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| Project Period (FY) |
2009 – 2011
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| Keywords | インターフェース / インプラント / 骨 / 上皮 |
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| Research Abstract |
The purpose of this study was to achieve strong and sustainable interface between dental implant and oral tissue such as bone and gingival soft tissue.
The interface between soft tissue and titanium was supposed to be weaker than tooth. The hydrothermal treatment of titanium under the presence of divalent cation enhanced adhesion of both epithelial and fibroblastic cells.
In regard to the bone-titanium interface, statins with PLGA microsphere as a carrier enhanced osteogenesis around the implant. Divalent cation treatment of titanium also enhanced bone-titanium contact.
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