2012 Fiscal Year Final Research Report
Study for preventing epidemic of viral zoonoses in Japan and theAmerican Continents
Project/Area Number |
21405035
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 海外学術 |
Research Field |
Applied veterinary science
|
Research Institution | Hokkaido University |
Principal Investigator |
KARIWA Hiroaki 北海道大学, 大学院・獣医学研究科, 准教授 (70224714)
|
Co-Investigator(Kenkyū-buntansha) |
ARIKAWA Jiro 北海道大学, 大学院・医学研究科, 教授 (10142704)
YOSHII Kentaro 北海道大学, 大学院・獣医学研究科, 助教 (50421988)
MORIMATSU Kumiko 北海道大学, 大学院・医学研究科, 准教授 (90220722)
|
Project Period (FY) |
2009 – 2012
|
Keywords | 人獣共通感染症 / ハンタウイルス / ウエストナイルウイルス / げっ歯類 / 鳥類 |
Research Abstract |
Three novel hantaviruses were detected in Mexican rodents. The antibody detection method for various hantavirus infections was developed. Five of six monoclonal antibodies to nucleocapsid protein (NP) of Mexican hantavirus were broadly reacted with NPs of rodent-borne hantaviruses. Glycosylation of West Nile virus E protein made great influence in the pathogenesis in chicks infected with West Nile virus.
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