2011 Fiscal Year Final Research Report
Study of PPCPs in Eastern Asian countries
| Project/Area Number |
21406005
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Environmental pharmacy
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| Research Institution | Hiroshima International University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OHTA Shigeru 広島大学, 大学院・医歯薬学総合研究科, 教授 (60160503)
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| Co-Investigator(Renkei-kenkyūsha) |
KITAMURA Shigeyuki 日本薬科大学, 薬学部, 教授 (40136057)
NISHIJIMA Wataru 広島大学, 環境安全センター, 教授 (20243602)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 環境汚染 / 医薬品 / 東アジア / 生態毒性 |
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| Research Abstract |
The aquatic environmental pollution by the pharmaceuticals has been investigated in Eastern Asian countries. The studies were carried out as joint research with local universities in Indonesia, Airlangga University and South Korea, Pusan University. Some pharmaceuticals were detected in the local rivers and effluent of sewage treatment plants. The reseach cooperation was developed.
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[Journal Article] Prediction of in vive hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver2012
Author(s)
Sanoh, Seigo ; Horiguchi, Aya ; Sugihara, Kazumi ; Kotake, Yaichiro ; Tayama, Yoshitaka ; Ohshita, Hiroki ; Tate noo, Chise ; Horie, Toni ; Kitamura, Shigeyuki ; Ohta, Shigeru
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Journal Title
Drug Metabolism & Disposition
Volume: 40(2)
Pages: 322-328
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[Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver2010
Author(s)
Nurrochmad, Ariel ; Ishii, Yuji ; Nakanoh, Hitomi ; Inoue, Tae ; Horie, Torn ; Sugihara, Kazumi ; Ohta, Shigeru ; Taketomi, Akinobu ; Maehara, Yoshihiko ; Yamada, Hideyuki
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Journal Title
Drug Metabolism and Pharmacokinetics
Volume: 25(3)
Pages: 262-373
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[Journal Article] Disruption of thyroid hormone function by environmental pollutants2009
Author(s)
Kashiwagi, Keiko ; Furuno, Nobuaki ; Kitamura, Shigeyuki ; Ohta, Shigeru ; Sugihara, Kazumi ; Utsumi, Kozo ; Hanada, Hideki ; Taniguchi, Kikuyo ; Suzuki, Ken-ichi ; Kashiwagi, Akihiko
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Journal Title
Journal of Health Science
Volume: 55(2)
Pages: 147-160
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