2011 Fiscal Year Final Research Report
Comprehensive and biological analysis of glycosphingolipid function expressed on cell using bioinformatics technique
| Project/Area Number |
21500293
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bioinformatics/Life informatics
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| Research Institution | National Research Institute for Child Health and Development |
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Principal Investigator |
NAKAJIMA Hideki 独立行政法人国立成育医療研究センター, 小児血液・腫瘍研究部, 研究員 (30450620)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 糖鎖 / 情報工学 / マイクロアレイ / 生体分子 / 細胞 / 組織 |
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| Research Abstract |
The data processing software of liquid chromatography-mass spectrometer(LC-MS) was developed and the software was applied for the analysis of glycolipid expression in some different types of infantile leukemia cell. Each different type of leukemia cells was categorized using the software by the statistical analysis of glycosphingolipid expression. Especially, new glycosphingolipid marker, Ln3Cer could be discovered in some type of leukemia cell using the software analysis.
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