2011 Fiscal Year Final Research Report
Temperature receptors in treatment of neurogenic bladder
| Project/Area Number |
21500479
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kagoshima University |
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Principal Investigator |
YOSHIDA Akira 鹿児島大学, 医歯学総合研究科, 助教 (40347109)
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| Co-Investigator(Kenkyū-buntansha) |
IKEDA Satoshi 鹿児島大学, 医学部・歯学部附属病院, 講師 (00343369)
OOWATASHI Akihiko 鹿児島大学, 医学部, 助教 (30295282)
KAWAHIRA Kazumi 鹿児島大学, 大学院・医歯学総合研究科, 教授 (20117493)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 温熱 / ラズベリーケトン / ラット / シストメトリー |
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| Research Abstract |
We investigated the effect of warming on detrusor smooth muscle contraction and the effect of warming and intravesical infusion of raspberry ketone on micturition reflex in rats. Warming inhibited high K and carbachol-induced contractions and reduced resting tension and amplitude of spontaneous contraction. Inhibition of carbachol. induced contraction was due to the inhibition of intracellular calcium mobilization. Warming tended to reduce pressure threshold for inducing micturition, micturition pressure and basal pressure. Intravesical infusion of raspberry ketone had no effect on micturition reflex.
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Research Products
(6 results)
