2012 Fiscal Year Final Research Report
A study on stress evaluation of the second hand smoke exposure by salivary catecholamine metabolites
Project/Area Number |
21500663
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Applied health science
|
Research Institution | Nippon Medical School |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
KAWADA Tomoyuki 日本医科大学, 医学(系)研究科(研究院), 教授 (00224791)
INAGAKI Hirofumi 日本医科大学, 医学部, 講師 (50213111)
HIRATA Yukiyo 日本医科大学, 医学部, 助教 (40322515)
HIRATA Kimiko 日本医科大学, 医学(系)研究科(研究院), その他 (70445815)
|
Project Period (FY) |
2009 – 2012
|
Keywords | 受動喫煙 / ストレス評価 / 唾液 / カテコールアミン代謝物 / HPLC 分析 |
Research Abstract |
The purpose of this study was to perform stress evaluation of the second hand smoke (SHS) exposure by salivary catecholamine metabolites. SHS exposure was surveyed by a questionnaire, and salivary cotinine level was measured for the nonsmokers. Then, the subjects were loaded with Uchida-Kraepelin test, and salivary cortisol and 3-Methoxy-4-hydroxyphenylglycol (MHPG) of catecholamine metabolite level was measured. Salivary MHPG level of a subject exposed to second hand smoke was significantly high after Uchida-Kraepelin test. Therefore, the salivary MHPG level was suggested to be valuable as a stress evaluation of second hand smoke exposure.
|