2011 Fiscal Year Final Research Report
Development of a specimen holder with a light source to realize highly efficient x-ray irradiation on biological cells
| Project/Area Number |
21540517
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Plasma science
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| Research Institution | Japan Atomic Energy Agency |
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Principal Investigator |
KADO Masataka 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 研究副主幹 (30360431)
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| Co-Investigator(Renkei-kenkyūsha) |
ISHINO Masahiko 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 研究副主幹 (80360410)
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| Project Period (FY) |
2009 – 2011
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| Keywords | プラズマ応用 / X線顕微鏡 |
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| Research Abstract |
We have developed a new specimen holder with a thin filmed gold target and observed live biological cells with flash exposure by realizing highly efficient x-ray irradiation. Comparing phase contrast images, fluorescent images, and soft x-ray images of the same biological cells directory, fine structures of cellular organelles have been analyzed. As a result strong correlation between cytoskeleton and mitochondria has been found and chromatin structures have been observed.
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