2011 Fiscal Year Final Research Report
Development of photo-functional proteins using photochromic molecules
| Project/Area Number |
21550049
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Organic chemistry
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| Research Institution | Kitasato University |
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Principal Investigator |
INADA Taeko 北里大学, 理学部, 講師 (60286375)
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| Project Period (FY) |
2009 – 2011
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| Keywords | フォトクロミック分子 / 機能性タンパク質 |
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| Research Abstract |
Hen egg white lysozyme was modified at specific position with diarylethene and it was shown that the enzymatic kinetics were modulated reversibly according to photochromism of diarylethene moiety. Fluorescence switching systems in response to enzyme activity were designed. It was also studied structure-activity relationship and reaction dynamics.
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