• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2011 Fiscal Year Final Research Report

Development of Fluorescent Probes for the Detection of Various Angiogenesis Factors and Their Application to Medical Diagnostics

Research Project

  • PDF
Project/Area Number 21560814
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biofunction/Bioprocess
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

SUZUKI Yoshio  独立行政法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 (60321907)

Project Period (FY) 2009 – 2011
Keywordsバイオセンサー
Research Abstract

Design and synthesis of fluorescent probes for the detection of angiogenesis was carried out based on the knowledge obtained by the development of fluorescent reagents for the detection of proteins. As a result, molecular probes for the detection of VEGF constructed by peptides and fluorescent molecules were developed, and the highly sensitive and easy detection of VEGF was successful with the use of nano-pillar substrates.

  • Research Products

    (13 results)

All 2012 2011 2010 2009

All Journal Article (5 results) (of which Peer Reviewed: 4 results) Presentation (7 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Development of Functional Fluorescent Molecular Probes and Their Biological Applications2011

    • Author(s)
      鈴木祥夫、横山憲二
    • Journal Title

      Encyclopedia of Nanoscience and Nanotechnology

      Volume: Vol.18 Pages: 1-20

    • Peer Reviewed
  • [Journal Article] Construction of a more sensitive fluorescence sensing material for the detection of vascularendothelial growth factor, a biomarker for angiogenesis, prepared by combining a fluorescent peptide and a nanopillar substrate2011

    • Author(s)
      鈴木祥夫、横山憲二
    • Journal Title

      Biosensors and Bioelectronics

      Volume: Vol.26 Pages: 3696-3699

    • DOI

      DOI:10.1016/j.bios.2011.02.007

    • Peer Reviewed
  • [Journal Article] Design and Synthesis of New Fluorescent Probe for Rapid and Highly Sensitive Detection of Proteins via Electrophoretic Gel Stain2011

    • Author(s)
      鈴木祥夫、高木信幸、千室智之、篠原淳、坂口菜央、平塚淳典、横山憲二
    • Journal Title

      Electrophoresis

      Volume: Vol.32 Pages: 1403-1413

    • DOI

      DOI:10.1002/elps.201000691

    • Peer Reviewed
  • [Journal Article] 血管内皮細胞増殖因子(VEGF)を検出するための蛍光ペプチドの創製2011

    • Author(s)
      鈴木祥夫、横山憲二
    • Journal Title

      細胞

      Volume: Vol.43 Pages: 32-33

  • [Journal Article] Development of a Fluorescent Peptide for the Detection of Vascular Endothelial Growth Factor(VEGF)2009

    • Author(s)
      鈴木祥夫、横山憲二
    • Journal Title

      ChemBioChem

      Volume: Vol.10 Pages: 1793-1795

    • DOI

      DOI:10.1002/cbic.200900190

    • Peer Reviewed
  • [Presentation] タンパク質を分光光学的に検出するための機能性材料の創製、「ナノ構造・物性」2012

    • Author(s)
      鈴木祥夫
    • Organizer
      第四回研究会
    • Place of Presentation
      神戸
    • Year and Date
      2012-01-20
  • [Presentation] メロシアニン構造を有する新規蛍光分子プローブを利用したタンパク質の高感度分析2011

    • Author(s)
      鈴木祥夫、横山憲二
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-09-15
  • [Presentation] Novel Fluorescent Reagents for High-Throughput and Highly-Sensitive In-Gel Protein Detection and Their Application to Proteomic Research2011

    • Author(s)
      鈴木祥夫、高木信幸、千室智之、篠原淳、坂口菜央、横山憲二
    • Organizer
      HUPO2011
    • Place of Presentation
      スイス
    • Year and Date
      2011-09-05
  • [Presentation] メロシアニン骨格を有する新規タンパク質検出用蛍光分子プローブの創製とSDS-PAGEへの応用2011

    • Author(s)
      鈴木祥夫、横山憲二
    • Organizer
      日本プロテオーム学会2011年大会
    • Place of Presentation
      新潟
    • Year and Date
      2011-07-28
  • [Presentation] Development of Fluorescent Reagents for the Detection of Proteins and Their Application to High-throughput Protein Analysis2010

    • Author(s)
      鈴木祥夫、横山憲二
    • Organizer
      Pacifichem2010
    • Place of Presentation
      ハワイ
    • Year and Date
      2010-12-17
  • [Presentation] 血管内皮細胞増殖因子(VEGF)を検出するための蛍光ペプチドの創製2010

    • Author(s)
      鈴木祥夫、横山憲二
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-25
  • [Presentation] 血管内皮細胞増殖因子(VEGF)検出用蛍光分子プローブの創製とナノピラーアレイ上における検出2010

    • Author(s)
      鈴木祥夫、横山憲二
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-17
  • [Patent(Industrial Property Rights)] タンパク質を検出するための分析試薬2010

    • Inventor(s)
      鈴木祥夫、横山憲二
    • Industrial Property Rights Holder
      (独)産業技術総合研究所
    • Industrial Property Number
      特許、特願2010-170805
    • Filing Date
      2010-07-29

URL: 

Published: 2013-07-31  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi