2011 Fiscal Year Final Research Report
Isolation and analyses of novel regulatory factors in differentiation of blood islands of frog embryo
| Project/Area Number |
21570220
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | Niigata University |
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Principal Investigator |
MAENO Mitsugu 新潟大学, 自然科学系, 准教授 (10190315)
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| Co-Investigator(Kenkyū-buntansha) |
KATO Takashi 早稲田大学, 教育・総合科学学術院, 教授 (80350388)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 器官形成 |
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| Research Abstract |
The physiological and biochemical properties of Val and Rdd proteins found in the Xenopus embryo have been investigated. We examined the biological activity and biochemical property of the various deletion mutants of Val. We also examined the association of Rdd proteins in the vascular system in the developing embryo. Furthermore, two distinct origins and differential regulations of primitive myeloid cells appeared in the tailbud embryo have been analyzed.
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[Journal Article] Distinct mechanisms control the timing of differentiation of two myeloid populations in Xenopus ventral blood islands2012
Author(s)
Maeno, M., Komiyama, K., Matsuzaki, Y., Hosoya, J., Kurihara, S., Sakata, H., Izutsu, Y.
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Journal Title
Dev. Growth Differ
Volume: 54
Pages: 187-201
Peer Reviewed
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[Journal Article] A novel approach for a toxicity prediction model of environmental pollutants by using a quantitative structure-activity relationship method based on toxicogenomics2011
Author(s)
Hosoya, J., Tamura, K., Muraki, N., Okumura, H., Ito, T., Maeno, M.
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Journal Title
ISRN Toxicology Article
Pages: 9
Peer Reviewed
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[Journal Article] Identification of erythroid progenitors induced by erythropoietic activity in Xenopus laevis2011
Author(s)
Nogawa-Kosaka, N., Sugai, T., Nagasawa, K., Tanizaki, Y., Meguro, M, Aizawa, Y., Maekawa, S., Adachi, M., Kuroki, R. and Kato, T
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Journal Title
J Exp Biol.
Volume: 214
Pages: 921-927
Peer Reviewed
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[Journal Article] Structural and biological properties of erythropoietin in Xenopus laevis2010
Author(s)
Nogawa-Kosaka, N., Hirose, T., Kosaka, N., Aizawa, Y., Nagasawa, K., Uehara, N., Miyazaki, H., Komatsu, N. and Kato, T.
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Journal Title
Exp. Hematol
Volume: 38
Pages: 363-372
Peer Reviewed
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[Journal Article] The keratin-related Ouroboros proteins function as immune antigens mediating tail regression in Xenopus metamorphosis2009
Author(s)
Mukaigasa, K., Hanasaki, A., Maeno, M., Fujii, H., Hayashida, S., Itoh, M., Kobayashi, M., Tochinai, S., Hatta, M., Iwabuchi, K., Taira, M., Onoe, K. and Izutsu, Y.
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Journal Title
Proc. Natl. Acad. Sci. USA
Volume: 106
Pages: 18309-18314
Peer Reviewed
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