2011 Fiscal Year Final Research Report
Development of Needle-type Ultra Micro Potentiometric Immunosensor Using Artificial Antibody Based on Morecularly Imprinted Polymer
| Project/Area Number |
21590048
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Physical pharmacy
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| Research Institution | Kyoto Pharmaceutical University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Keywords | 分子インプリントポリマー / プラズマ重合膜 / 免疫センサー / ヒスタミン |
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| Research Abstract |
A potentiometric artificial immunosensor was developed by using artificial antibody based on molecularly imprinted polymer using histamine as a model template. The sensor consists of a rod-type graphite electrode functioning as a transducer and molecularly imprinted polymer absorbed in the plasma-polymer thin layer functioning as a sensing element. The sensor was found to have superior selectivity and specificity to histamine.
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