2011 Fiscal Year Final Research Report
Identification of the virulence factors associated with Helicobacter heilmannii-induced gastric MALT lymphoma
Project/Area Number |
21590491
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Bacteriology (including Mycology)
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Research Institution | Kitasato University |
Principal Investigator |
MATSUI Hidenori 北里大学, 大学院・感染制御科学府, 講師 (30219373)
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Project Period (FY) |
2009 – 2011
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Keywords | Helicobacter heilmannii / 胃MALTリンパ腫 / ゲノム解析 |
Research Abstract |
The genomic DNA was prepared from gastric homogenates of mice infected with H. heilmannii TKY or H. suis SNTW10 by using immunomgnetic beads(Sepa-Max Hp). Greater than 110 bases were sequenced of each strain by ABI SOLiD 4 system. Comparative analysis of newly sequenced genomes to the existing reference genomes of Helicobacter species enabled the identification of several H. heilmannii-specific virulence genes.
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Research Products
(10 results)
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[Presentation] Molecular mechanism of gastric MALT lymphoma formation by Helicobacter heilmannii infection2011
Author(s)
Takahashi, T., Matsui, H., Takizawa A, Takahashi, S., Hibi, T., Nakamura, M., and Tsuchimoto, K
Organizer
Digestive Disease Week(DDW) 2011
Place of Presentation
Chicago IL, USA
Year and Date
2011-05-07
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