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2011 Fiscal Year Final Research Report

Novel Marker of oxidative stress by new radical trap agent

Research Project

  • PDF
Project/Area Number 21590633
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Laboratory medicine
Research InstitutionKyushu University of Health and Welfare

Principal Investigator

SATO Keizo  九州保健福祉大学, 薬学部, 教授 (00315293)

Project Period (FY) 2009 – 2011
Keywords臨床 / 医療・福祉 / 薬学 / 感染症
Research Abstract

We found that Novel Marker of oxidative stress by new radical trap agent using our developed new spin trap agent, 5-diphenylphosphoryl-5-methyl-pyrroline-N-Oxide(DPPMPO). It is very useful for free radical detection in not only chemical, cellular, enzymatical system but also in vivo human system by using ESR spin trap extraction method with DPPMPO.

  • Research Products

    (9 results)

All 2012 2011

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (5 results)

  • [Journal Article] Effects of lecithinized superoxide dismutase and/or pirfenidone against bleomycin-induced pulmonary fibrosis2012

    • Author(s)
      Tanaka K, Azuma A, Miyazaki Y, Sato K, Mizuhisma T
    • Journal Title

      Chest

      Volume: (in press)

    • Peer Reviewed
  • [Journal Article] In vivo evidence of free radical generation in the mouse lung after exposure to Pseudomonas aeruginosa bacterium : an ESR spin-trapping investigation2012

    • Author(s)
      Sato K, Corbett J, Mason RP, Kadiiska MB
    • Journal Title

      Free Radic Res

      Volume: 46巻 Pages: 645-55

    • Peer Reviewed
  • [Journal Article] Phosphoenoipyruvic Acid, an Intermediary Metabolite of Glycolysis, as a Potential Cytoprotectant and Anti-oxidant in Hela Cells2012

    • Author(s)
      Kondo Y, Ishithuka Y, Kadowaki D, Kuroda M, Tanaka Y, Nagatomi M, Irikura M, Hirata S, Sato K, Maruyama T, Hamasaki N, and Irie T
    • Journal Title

      Biol. Pharm. Bull

      Volume: 35巻 Pages: 1-6

    • Peer Reviewed
  • [Journal Article] Therapeutic effect of lecithinized superoxide dismutase on pulmonary emphysema2011

    • Author(s)
      Tanaka K, Tanaka Y, Miyazaki Y, Namba T, Sato K, Aoshiba K, Azuma A, Mizushima T
    • Journal Title

      J PharmacolExpTher

      Volume: 338巻 Pages: 810-818

    • Peer Reviewed
  • [Presentation] リウマチ性疾患と肺病変2011

    • Author(s)
      佐藤圭創
    • Organizer
      福岡地区リウマチ教育研修会
    • Place of Presentation
      福岡
    • Year and Date
      2011-12-11
  • [Presentation] 感染症の現在・過去・未来-病態を考えた未来の感染症治療を目指して-2011

    • Author(s)
      佐藤圭創
    • Organizer
      第21回日本耳科学会総会・学術講演会
    • Place of Presentation
      沖縄
    • Year and Date
      2011-11-24
  • [Presentation] マクロライドの新作用としての気道炎症抑制作用2011

    • Author(s)
      佐藤圭創
    • Organizer
      生体機能と創薬シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-09-01
  • [Presentation] 呼吸器感染における炎症抑制の最前線2011

    • Author(s)
      佐藤圭創
    • Organizer
      第59回日本化学療法学会総会イブニングセミナー4
    • Place of Presentation
      札幌
    • Year and Date
      2011-06-24
  • [Presentation] インフルエンザの劇症化機序とマクロライドの役割2011

    • Author(s)
      佐藤圭創
    • Organizer
      第73回耳鼻咽喉科臨床学会総会・学術講演会
    • Place of Presentation
      長野
    • Year and Date
      2011-06-24

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Published: 2013-07-31  

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