2011 Fiscal Year Final Research Report
Study on discharged antimicrobials into aquatic environment and presence of antimicrobial-resistant organisms
| Project/Area Number |
21590684
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Nagasaki University |
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Principal Investigator |
OKUMURA Junko 長崎大学, 熱帯医学研究所, 准教授 (40323604)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Satoshi 国立国際医療センター, 熱帯医学・マラリア研究部, 室長 (40207874)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 薬剤耐性 / 抗生剤 / 環境水 |
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| Research Abstract |
This study revealed the following four points. Firstly, the environment where we live has been polluted with antimicrobials and the concentrations were less than detection limit by LC-MS/ MS. Secondly, there was possibility that antimicrobials could not appropriately removed at water-treatment plants. Thirdly, the isolated gram-negative bacilli showed resistance to antimicrobials whose concentrations were undetectable by LC-MS/ MS. Fourthly, quite a few bacilli were not sensitive to Quinolones and Carbapenems, and these MDROs might threaten human health.
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