2011 Fiscal Year Final Research Report
Pancreatic diseases in metabolic syndrome
Project/Area Number |
21590877
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Gastroenterology
|
Research Institution | Nagoya University of Arts and Sciences |
Principal Investigator |
KITAGAWA Motoji 名古屋学芸大学, 管理栄養学部, 教授 (80262898)
|
Project Period (FY) |
2009 – 2011
|
Keywords | メタボリックシンドローム / 内臓脂肪型肥満 / 膵脂肪置換 / アディポネクチン |
Research Abstract |
Pancreatic diseases in subjects with excess visceral adipose tissue were evaluated by pancreatic images by abdominal computed tomography(CT) and serum markers. Fat deposition or pancreatic atrophy was detected in 19% of subjects with the amount of visceral fat area(VFA)≧100cm^<2>, and in only 2% of subjects with VFA<100cm^<2>. Excess visceral adipose tissue may cause pancreatic fat deposition. Subjects with VFA≧100cm^<2> had significant lower levels of serum amylase and adiponectin than subjects with VFA<100cm<2>. Exocrine and endocrine pancreatic damages should be elucidated in subjects with excess visceral adipose tissue.
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