2011 Fiscal Year Final Research Report
Impact of exercise therapy on regression of coronary atherosclerotic plaque
| Project/Area Number |
21590910
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Juntendo University |
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Principal Investigator |
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| Research Collaborator |
MIYAUCHI Katsumi 順天堂大学, 医学部, 先任准教授 (60200119)
SHIMADA Kazunori 順天堂大学, 医学部, 准教授 (60327814)
NISHITANI Miho 順天堂大学, 医学部, 助教 (60407301)
KOBA Shinji 昭和大学, 医学部, 講師 (20276546)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 急性冠症候群 / 血管内超音波 / 冠動脈プラーク / 血管リモデリング / 包括的心臓 / リハビリテーション / 身体活動量 |
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| Research Abstract |
We investigated the effects of comprehensive cardiac rehabilitation (CR) on coronary plaque volume changes and vascular remodeling in patients after acute coronary syndrome (ACS). We enrolled 41 consecutive patients after ACS and patients were divided into the CR (16 patients) and the non-CR group (25 patients). Plaque volume and vascular remodeling were not significantly changed in the two groups during 6 months. However, percent change in plaque volume showed a significant negative correlation with daily physical activity. Intensive physical activity may result in coronary plaque regression in patients after ACS.
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