2011 Fiscal Year Final Research Report
Regulation of lipid composition of breast milk during lactation
| Project/Area Number |
21591336
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Osaka Medical College |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TAMAI Hiroshi 大阪医科大学, 医学部, 教授 (30179874)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 母乳 / 脂質 / ビタミンE / 核内受容体 |
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| Research Abstract |
Nutrition of breast-feeding is the most appropriate of all available milks for human infants. Human milk contains secretary IgA antibodies, lysozyme, and lactofarin, which provide gastrointestinal immunity. The composition of breast milk including minerals, prorotein and fats is changed during laction, however, the regulation of them have remained to be elucidated. In the study, the ligand of liver X receptor(LXR), one of nuclear receptor superfamily may affect the lipid contents of breast milk. This result The transcriptional factors including nuclear receptors may involve components of breast milk during lactation.
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[Journal Article] Peroxisome proliferation activation receptor alpha modulation of Ca2+-regulated exocytosis via arachidonic acid in guinea-pig antral mucous cells2010
Author(s)
Sawabe Y, Shimamoto C, Sakai A, Kuwabara H, Saad AH, Nakano T, Takitani K, Tamai H, Mori H, Marunaka Y, Nakahari T.
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Journal Title
Exp Physiol
Volume: 95(8)
Pages: 858-68
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