2011 Fiscal Year Final Research Report
Development and the etiology investigation of the effective cure of the Kawasaki disease : Molecular genetic base and proteome analysis
| Project/Area Number |
21591397
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKAHATA Yayoi 北里大学, 医学部, 講師 (20306591)
KIMURA Sumito 北里大学, 医学部, 助教 (40365151)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 小児循環器学 |
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| Research Abstract |
It was proved that combination of immunoglobulin therapy and steroid pulse therapy was clinically effective as primary care for the intractable Kawasaki disease by a randomness prospective competitive examination. I inspected the mechanism of this effective cure by molecular genetic technique at the same time. In addition, the effectiveness of the stratification score of the intractable Kawasaki disease was inspected in a molecular genetic study. I developed the cure for the example which start of therapy was late for. It is suggested that some kind of viral infection affects it about the etiology and is studying it continuously.
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