2011 Fiscal Year Final Research Report
Multilateral analysis of Neuregulin-1 function in schizophrenia patients.
| Project/Area Number |
21591491
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Nara Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NORIYAMA Yoshinobu 奈良県立医科大学, 医学部, 博士研究員 (20305725)
KIUCHI Kuniaki 奈良県立医科大学, 医学部, 助教 (20398449)
TAOKA Toshiaki 奈良県立医科大学, 医学部, 准教授 (30305734)
TSUBOI Akio 奈良県立医科大学, 医学部, 教授 (20163868)
MAKINODAN Manabu 奈良県立医科大学, 医学部, 助教 (00510182)
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| Project Period (FY) |
2009 – 2011
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| Keywords | ニューレグリン / 統合失調症 / 末梢神経伝導速度 / 拡散テンソル画像 / iPS細胞 |
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| Research Abstract |
Neuregulin-1 is a kind of growth factors which promotes neuronal and oligodendroglial growth and differentiation, and known as a candidate gene(HapICE) for schizophrenia. To investigate how this gene affects the disease, we started genetic analysis of 201 patients and 203 control subjects, followed by Diffusion Tensor Imaging and measurement of peripheral nerve conduction velocity.
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