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2011 Fiscal Year Final Research Report

Evaluation of hemodynamic changes in pulmonary and systemic arterial circulation with special attention to shunt volume in patients with pulmonary fibrosis using phase contrast MRI.

Research Project

  • PDF
Project/Area Number 21591570
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionUniversity of the Ryukyus

Principal Investigator

MURAYAMA Sadayuki  琉球大学, 大学院・医学研究科, 教授 (60239548)

Co-Investigator(Kenkyū-buntansha) KAKINOHANA Yasumasa  琉球大学, 大学院・医学研究科, 助教 (20185713)
KAMIYA Hisashi  琉球大学, 大学院・医学研究科, 助教 (60363678)
Project Period (FY) 2009 – 2011
Keywords肺高血圧 / MRI / Velocity-encoded cine MRI / 肺動脈血流
Research Abstract

Using PC-MRI, we calculated various indexes of the pulmonary blood flow of the patients that pulmonary hypertension should have been suspected and examined correlation with the echocardiographic tricuspid gradient. As a result, an average area of the pulmonary artery truncus, minimum area, and a maximal area a were well correlated with tricuspid gradient. It was minimum area to have been the strongest in a correlation ;(coefficient of correlation 0. 772 ; p=0. 001). Secondly, an aortic and pulmonary arterial flow by PC-MRI for normal volunteers and patients with interstitial pneumonia were calculated both during free breathing and respiratory breath-holding. Both flow significantly decreased in normal volunteers and patients. However, in patients, no significant reduction under the breath-holding nor increase of bronchopulmonary shunt were observed.

  • Research Products

    (3 results)

All 2012 2011

All Presentation (3 results)

  • [Presentation] Phase-contrast MRIを用いた肺高血圧症の評価-心臓超音波検査による三尖弁圧較差との相関の検討-2012

    • Author(s)
      椿本真穂、土屋奈々絵、鮎川雄一郎、村山貞之、安隆則
    • Organizer
      第4回呼吸機能イメージング研究会学術集会
    • Place of Presentation
      滋賀県,ピアザ淡海、琵琶湖ホテル
    • Year and Date
      20120210-11
  • [Presentation] Evaluation of Hemodynamic Changes in Pulmonary and Systemic Arterial Circulation in Patients with Pulmonary Fibrosis in Relation to Breathing Methods Using. Phase Contrast MRI2011

    • Author(s)
      Nanae Tsuchiya, Yuichiro Ayukawa, Sadayuki Murayama
    • Organizer
      Joint Meeting combining The 3rd meeting of the Japanese Society of Pulmonary Functional Imaging and 5th International Workshop for Pulmonary Functional Imaging
    • Place of Presentation
      兵庫県、兵庫県淡路夢舞台国際会議場
    • Year and Date
      20110128-30
  • [Presentation] Phase-contrast MRIによる肺血流評価と肺動脈圧の関連性2011

    • Author(s)
      土屋奈々絵、鮎川雄一郎、村山貞之、安隆則
    • Organizer
      第112回沖縄県医師会医学会総会
    • Place of Presentation
      沖縄県,沖縄県医師会館
    • Year and Date
      2011-06-12

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Published: 2013-07-31  

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