The role of autophagy in the differentiation of T cells in the thymic epithelial tumors

2011 Fiscal Year Final Research Report

• Project/Area Number: 21591813
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Thoracic surgery
• Research Institution: 独立行政法人国立病院機構近畿中央胸部疾患センター(臨床研究センター) (2011); Clinical Research Center, National Hospital Organization, Kinki-Chuo Chest Medical Center (2010); Osaka University (2009)
• Principal Investigator: UTSUMI Tomoki 独立行政法人国立病院機構近畿中央胸部疾患センター(臨床研究センター), 呼吸器外科, 医長 (40423165)
• Co-Investigator(Kenkyū-buntansha): OKUMURA Meinoshin 大阪大学, 医学系研究科, 教授 (40252647) ; MINAMI Masato 大阪大学, 医学部附属病院, 准教授 (10240847) ; SAWABATA Noriyoshi 大阪大学, 医学系研究科, 准教授 (50403184) ; INOUE Masayoshi 大阪大学, 医学系研究科, 講師 (10379232) ; KADOTA Yoshihisa 大阪大学, 医学系研究科, 助教 (50464243) ; SHIGEMURA Norihisa 大阪大学, 医学系研究科, 助教 (30505508) ; TOKUNAGA Toshiteru 大阪大学, 医学部・附属病院, 医員 (70448059) ; IDEGUCHI Kan 大阪大学, 医学部・附属病院, 医員 (60448058)
• Project Period (FY): 2009 – 2011
• Keywords: 縦隔外科学

Research Abstract

Thymoma tissues were accumulated from the surgical specimens to investigate phenotype of lymphocyte markers, expression of autophagy-related genes and histological cell types. There were no apparent relationships between 3 studied autophagy-related genes and clinical characteristics of thymomas, lymphocyte phenotypes, and histological cell types.