2011 Fiscal Year Final Research Report
Preclinical trial of less invasive synovial stem cell therapy using a pig knee articular cartilage defect model
| Project/Area Number |
21591937
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
MUNETA Takeshi 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 (50190864)
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| Co-Investigator(Kenkyū-buntansha) |
SEKIYA Ichiro 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 (10345291)
KOBAYASHI Eiji 自治医科大学, 医学部, 教授 (00245044)
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| Project Period (FY) |
2009 – 2011
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| Keywords | H :運動器外傷学 |
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| Research Abstract |
Less invasive synovial stem cell transplantation promoted healing of a full-thickness articular cartilage defect at weight-bearing area in a mini pig model. The results facilitate to perform clinical trial of the transplantation on human patients with articular cartilage injury.
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[Journal Article] Arthroscopic, histological and MRIanalyses of cartilage repair after aminimally invasive method oftransplantation of allogeneic synovialmesenchymal stromal cells into cartilagedefects in pigs2012
Author(s)
Nakamura T, Sekiya I, Muneta T, Hatsushika D, Horie M, Tsuji K, Kawarasaki T, Watanabe A, Hishikawa S, Fujimoto Y, Tanaka H, Kobayashi E
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Journal Title
Cytotherapy
Volume: 14
Pages: 327-338
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[Presentation] Synovial Mesenchymal Stem Cells Transplantation Contributes to Cartilage Regeneration in Porcine Model2011
Author(s)
Nakamura T, Sekiya I, Hatsushika D, Horie M, Tsuji K, Muneta T, Kawarasaki T, Watanabe A, Hishikawa S, Fujimoto Y, Tanaka H, Kobayashi E.
Organizer
Orthopaedic ResearchSociety 2011
Place of Presentation
Long Beach
Year and Date
20110113-16
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