2011 Fiscal Year Final Research Report
Implantation of autologous bone marrow cells has a potential to be treatments for radiotherapy-induced bladder dysfunction
| Project/Area Number |
21592069
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Shinshu University |
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Principal Investigator |
KATO Haruaki 信州大学, 医学部・附属病院, 講師 (90233808)
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| Research Collaborator |
IMAMURA Tetsuya 信州大学, 医学部, 助教 (00467143)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 再生医療 / 放射線照射療法 / 排尿障害 / 骨髄由来細胞 |
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| Research Abstract |
We determined if implantation of bone marrow-derived cells has a potential to be treatments for radiotherapy-induced bladder dysfunction. The cell implantation reconstructed smooth muscle layers and nerve fibers. The cell-implanted urinary bladders recovered regular voiding intervals and low residual volume, which were similar to non-irradiated normal bladder function.
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[Journal Article] A new Ehlers-Danlos syndrome with craniofacial characteristics, multiple congenital contractures, progressive joint and skin laxity, and multisystem fragility-related manifestations.2010
Author(s)
Kosho T, Miyake N, Hatamochi A, Takahashi J, Kato H, Miyahara T, Igawa Y, Yasui H, Ishida T, Ono K, Kosuda T, Inoue A, Kohyama M, Hattori T, Ohashi H, Nishimura G, Kawamura R, Wakui K, Fukushima Y, Matsumoto N.
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Journal Title
Am J Med Genet A
Volume: 152(A)
Pages: 1833-1846
DOI
Peer Reviewed
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