2011 Fiscal Year Final Research Report
Intraoperative diagnostic system for the metastasis of sentinel lymph node using the genetic technique
| Project/Area Number |
21592200
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
MATSUZUKA Takashi 福島県立医科大学, 医学部・耳鼻咽喉科学講座, 講師 (80336461)
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| Co-Investigator(Kenkyū-buntansha) |
KOGURE Michhiko 福島県立医科大学, 医学部, 講師 (90264548)
MIURA Tomohiro 福島県立医科大学, 医学部, 助教 (00423806)
SUZUKI Masahiro 福島県立医科大学, 医学部, 助手 (90513268)
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| Project Period (FY) |
2009 – 2011
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| Keywords | センチネルリンパ節 |
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| Research Abstract |
One-step nucleic acid amplification(OSNA) is a new automated rapid system to detect lymph node metastasis using the genetic technique. The purpose of this study was to develop the OSNA method to identify lymph node metastasis in head and neck cancer.
Analysis of 22 cases of head neck squamous cell carcinoma was performed with OSNA method and with routine histological examination. The OSNA and histological results were identical. According to this study, OSNA method has the potential to diagnose cervical node metastasis in head and neck cancer.
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