2011 Fiscal Year Final Research Report
Study of evolution of osteoclasts regulating factors in teleost fish
| Project/Area Number |
21592319
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
DOMON Takanori 北海道大学, 大学院・歯学研究科, 教授 (50217618)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIMURA Yoshitaka 北海道大学, 大学院・歯学研究科, 助教 (30230816)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 口腔解剖学(含組織学・発生学) |
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| Research Abstract |
The origin of osteoclasts resorbing bone remains unknown. Bone tissue is seen on teleost fish in phylogeny, and there old osteoclasts would be seen. The present study established the culture system of isolated Japanese medaka and observed their structure by light-and electron microscopy. The cultured cells showed no resorptive lacuna but etched surfaces on sperm whale dentine. These results may be related to the evolution of regulating fac tors of osteoclasts.
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