2011 Fiscal Year Final Research Report

Higher biofunctional nano-surface modification for development of histocompatibility typed titanium implants

Research Project

Project/Area Number	21592452
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Prosthetic dentistry
Research Institution	Hiroshima University
Principal Investigator	ABE Yasuhiko 広島大学, 病院, 講師 (00253097)
Co-Investigator(Kenkyū-buntansha)	HIASA Kyou 広島大学, 大学院・医歯薬学総合研究科, 助教 (60304432) HIRATA Isao 広島大学, 大学院・医歯薬学総合研究科, 助教 (40346507)
Project Period (FY)	2009 – 2011
Keywords	チタン / インプラント / 表面改質 / Hydroxylapatite / β-tricalcium phosphate / SPR解析 / ESCA分析
Research Abstract	Concerning titanium implant coated with hydroxyapatite, processing method to treat hydroxyapatite with 30% phosphoric acid for 10 minutes was established for modification of a nanostructured surface with a ratio of calcium to phosphorus analogous toβ-tricalcium phosphate. This higher biofunctional nano-surface modification could accelerate the proliferation and differentiation of osteoblast cells