2011 Fiscal Year Final Research Report
Regulation of periodontal tissue re-generation with combination use of FGF-2 and on-demand 3D shaped graft material
| Project/Area Number |
21592495
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
NOZAKI Takenori 大阪大学, 大学院・歯学研究科, 助教 (30263304)
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| Co-Investigator(Kenkyū-buntansha) |
KITAMURA Masahiro 大阪大学, 大学院・歯学研究科, 准教授 (10243247)
SAHO Teruyuki 大阪大学, 歯学部附属病院, 助教 (10263295)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 組織再生 / シグナル分子 / インプラント / FGF-2 |
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| Research Abstract |
It is confirmed that the combination use of FGF-2 and beta-TCP has a significant potential to promote periodontal tissue regeneration in an animal model study. Additionally, it is revealed that FGF-2 promotes osteogenesis and initial osseo-integration of implant with low primary stability. These results suggest that FGF-2 is a Signaling molecule suitable for on-demand 3D shaped transplant material which promotes tissue regeneration effectively
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