2011 Fiscal Year Final Research Report
Study of bone remodeling using mouse teeth movement model
| Project/Area Number |
21592611
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Orthodontic/Pediatric dentistry
|
|---|
| Research Institution | Ohu University |
|---|
Principal Investigator |
FUKAI Naomi 奥羽大学, 歯学部, 教授 (60134681)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MORO Yuriko 奥羽大学, 歯学部, 助教 (90433549)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
YAMATO Masayuki 東京女子医科大学, 医学部, 教授 (40711726)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | 歯科矯正学 / 骨リモデリング / マウス / 器官培養 |
|---|
| Research Abstract |
The mechanism of bone remodeling was studied using organ culture system in which mechanical force was given to a molar of mouse maxilla. Before an actual tooth movement was observed expression of col1 and estrogen receptor RNAs were changed just after a couple of hours after the stress was given. These results indicated that early molecular changes occurred and affected the bone remodeling.
|
