2011 Fiscal Year Final Research Report
Possibility of the oral microorganism control in the elderly by a gel-entrapped catechin
| Project/Area Number |
21592664
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Nihon University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
IMAI Kenichi 日本大学, 歯学部, 講師 (60381810)
OCHIAI Kuniyasu 日本大学, 歯学部, 教授 (50095444)
YAMADA Kiyoshi 日本大学, 歯学部, 助教 (30313076)
SENPUKU Hidenobu 国立感染症研究所, 技官 (20250186)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 口腔ケア |
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| Research Abstract |
Microbial inhibition zones against oral microorganisms using gel-entrapped catechin(GEC) were found for all of the strains of Actinomyces naeslundii, Streptococcus mutans, Candida albicans and periodontopathic bacteria in vitro assay. By contrast, no inhibitory effect was observed for oral streptococci which play an important role in indigenous oral flora. The anti-microbial activity of GEC is related with hydrogen peroxide. On the other hand, in vivo assay, same anti-microbial activity was observed by the application of GEC.
These results suggest that GEC could be useful for oral care in the elderly.
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