2011 Fiscal Year Final Research Report
Development of Chromogenic Probe/Dendrimer Complexes for Molecular Discrimination
| Project/Area Number |
21655030
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Analytical chemistry
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| Research Institution | Sophia University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ENDO Akira 上智大学, 理工学部, 准教授 (00119124)
HASHIMOTO Takeshi 上智大学, 理工学部, 助教 (20333049)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 糖鎖 / 識別機能 / アゾ色素 / 化学センサー / ボロン酸 / デンドリマー / 超分子 |
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| Research Abstract |
In this study, we have developed new types of sugar recognition systems based upon self-assembly of boronic acid azoprobes or ruthenium complexes on the surface of polyamide amine dendrimer(PAMAM). The generation of PAMAM and the sugar species were found to selectively affect the UV-vis and electrochemical responses of phenylboronic acid probe/dendrimer complexes, providing a novel chemosensor functioned in water.
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