2011 Fiscal Year Final Research Report
Development of Non-invasive Checkup Chip for Lifestyle-related Diseases by Molecular Imprinting
| Project/Area Number |
21680041
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
SHIIGI Hiroshi 大阪府立大学, 大学院・工学研究科, 准教授 (70335769)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 非侵襲計測 / 生活習慣病 / コレステロール / 分子鋳型 / センサ / バイオチップ |
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| Research Abstract |
Controlling the total cholesterol level is important for preventing lifestyle-related diseases. Therefore, a simple and non-invasive method of measuring skin cholesterol has been developed by using a molecularly imprinted self-assembled monolayer(SAM) sensor. Since the extracted solution from a skin was analyzed using a high-performance liquid chromatography and the molecularly imprinted SAM electrode, both results had a good correlation was found. A simple and non-invasive electrochemical sensor has been developed by using the molecularly imprinted SAM electrode with a high sensitivity and selectivity. A production of disposable sensor chip has been also examined to the practical application of the sensor
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