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2011 Fiscal Year Final Research Report

Dynamic nanocrystal clusters on compacted DNA structure by means of biomineralization

Research Project

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Project/Area Number 21686076
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Biofunction/Bioprocess
Research InstitutionTohoku University

Principal Investigator

UMETSU Mitsuo  東北大学, 大学院・工学研究科, 准教授 (70333846)

Project Period (FY) 2009 – 2011
Keywordsナノバイ / ナノ材料 / 生物・生体工学 / 自己組織化 / 分子認識
Research Abstract

DNA molecules have the properties of polymer electrolytes, and the condensation of cations on DNA causes the transition of DNA to globule structure. In this study, I combined the globule transition of DNA by means of metal ion and the biomineralization technique to form nanocrystals of metal, semiconductor, and ceramics on DNA globule structure. The assembled nanocrystals, further, were applied for electronanodevice and nanotranslocator.

  • Research Products

    (29 results)

All 2011 2010 2009 Other

All Journal Article (12 results) (of which Peer Reviewed: 12 results) Presentation (15 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Biomimetic engineering of modular bispecific antibodies for biomolecule immobilization2011

    • Author(s)
      Hideki Watanabe, Kengo Kanazaki, Takeshi Nakanishi, Hidenori Shiotsuka, Satoru Hatakeyama, Masaru Kaieda Takeshi Imamura, Mitsuo Umetsu, and Izumi Kumagai
    • Journal Title

      Langmuir

      Volume: 27 Pages: 9656-9661

    • Peer Reviewed
  • [Journal Article] Fabrication of Pd. DNA and Pd. CNT hybrid nanostructures for hydrogen sensors2011

    • Author(s)
      Satoshi Ohara, Yoshiharu Hatakeyama, Mitsuo Umetsu, Zhenquan Tan, and Tadafumi Adschiri
    • Journal Title

      Advanced Powder Technology

      Volume: 22 Pages: 559-565

    • Peer Reviewed
  • [Journal Article] One-pot Hydrothermal Synthesis of an Assembly of Magnetite Nanoneedles on a Scaffold of Cyclic-diphenylalanine Nanorods2011

    • Author(s)
      Takanari Togashi, Mitsuo Umetsu, Takashi Naka, Satoshi Ohara, Yoshiharu Hatakeyama, and Tadafumi Adschiri
    • Journal Title

      Journal of Nanoparticle Research

      Volume: 13 Pages: 3991-3999

    • Peer Reviewed
  • [Journal Article] Enhancement of cellulolytic enzyme activity by clustering of cellulose binding domain on nanoscaffolds2011

    • Author(s)
      Do-Myoung Kim, Mitsuo Umetsu, Kyo Takai, Takashi Matsuyama, Nobuhiro Ishida, Haruo Takahashi, Ryutaro Asano, and Izumi Kumagai
    • Journal Title

      Small

      Volume: 7 Pages: 656-664

    • Peer Reviewed
  • [Journal Article] Material-binding peptide application-ZnO crystal structure control by means of a ZnO-binding peptide-2011

    • Author(s)
      Takanari Togashi, Nozomi Yokoo, Mitsuo Umetsu, Satoshi Ohara, Takashi Naka, Seiichi Takami, Hiroya Abe, Izumi Kumagai, and Tadafumi Adschiri
    • Journal Title

      Journal of Bioscience and Bioengineering

      Volume: 111 Pages: 140-145

    • Peer Reviewed
  • [Journal Article] Direct immobilization of gold-binding antibody fragments for immunosensor applications2010

    • Author(s)
      Takahisa Ibii, Masaru Kaieda, Satoru Hatakeyama, Hidenori Shiotuka, Izumi Kumagai, Hideki Watanabe, Mitsuo Umetsu, and Takeshi Imamura
    • Journal Title

      Analytical Chemistry

      Volume: 82 Pages: 4229-4235

    • Peer Reviewed
  • [Journal Article] Continuous synthesis of fine MgFe2O4 nanoparticles by supercritical hydrothermal reaction2010

    • Author(s)
      Takafumi Sasaki, Satoshi Ohara, Takashi Naka, Jana Vejpravova, Vladimir Sechovsky, Mitsuo Umetsu, Seiichi Takami, Balachandran Jeyadevan, and Tadafumi Adschiri
    • Journal Title

      he Journal of Supercritical Fluids

      Volume: 53 Pages: 92-94

    • Peer Reviewed
  • [Journal Article] Protein-protein interactions and selection : generation of molecule-binding proteins on the basis of tertiary structural information2010

    • Author(s)
      Mitsuo Umetsu, Takeshi Nakanishi, Ryutaro Asano, Takamitsu Hattori, and Izumi Kumagai
    • Journal Title

      FEBS Journal

      Volume: 277 Pages: 2006-2014

    • Peer Reviewed
  • [Journal Article] High Affinity Anti-inorganic Material Antibody Generation by Integrating Graft and Evolution Technologies. POTENTIAL OF ANTIBODIES AS BIOINTERFACE MOLECULES2010

    • Author(s)
      Takamitsu Hattori, Mitsuo Umetsu, Takeshi Nakanishi, Takanari Togashi, Nozomi Yokoo, Hiroya Abe, Satoshi Ohara, Tadafumi Adschiri, and Izumi Kumagai
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 285 Pages: 7784-7793

    • Peer Reviewed
  • [Journal Article] Organic-ligand-assisted hydrothermal synthesis of ultrafine and hydrophobic ZnO nanoparticles2010

    • Author(s)
      Tahereh Mousavand, Satoshi Ohara, Takashi Naka, Mitsuo Umetsu, Seiichi Takami, and Tadafumi Adschiri
    • Journal Title

      Journal of Materials Research

      Volume: 25 Pages: 219-223

    • Peer Reviewed
  • [Journal Article] Direct and Selective Immobilization of Proteins by Means of an Inorganic Material-Binding Peptide : Discussion on Functionalization in the Elongation to Material-Binding Peptide2010

    • Author(s)
      Nozomi Yokoo, Takanari Togashi, Mitsuo Umetsu, Kouhei Tsumoto, Takamitsu Hattori, Takeshi Nakanishi, Satoshi Ohara, Seiichi Takami, Takashi Naka, Hiroya Abe, Izumi Kumagai, and Tadafumi Adschiri
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 114 Pages: 480-486

    • Peer Reviewed
  • [Journal Article] Palladium. polyelectrolyte hybrid nanoparticles for hydrogen sensor in fuel cells2009

    • Author(s)
      Satoshi Ohara, Yoshiharu Hatakeyama, Mitsuo Umetsu, Kazuyoshi Sato, Takashi Naka, and Tadafumi Adschiri
    • Journal Title

      Journal of Power Sources

      Volume: 193 Pages: 367-370

    • Peer Reviewed
  • [Presentation] Recombinant Protein Engineering for Biofunctionalization of nanomaterials2011

    • Author(s)
      Mitsuo Umetsu, T. Adschiri, I. Kumagai
    • Organizer
      Frontier 2011
    • Place of Presentation
      Sendai
    • Year and Date
      2011-12-06
  • [Presentation] DNA Compaction by Metal Complexes : Homogenous Spherical Mosslike Assembly by Pd Nanoclusters on Compacted DNA2011

    • Author(s)
      Mitsuo Umetsu, Yoshiharu Hatakeyama, Satoshi Ohara, Fumihiko Kawadai, Seiitch Takami, Takashi Naka, Tadafumi Adschiri
    • Organizer
      17th International Biophycise Congress (IUPAB)
    • Place of Presentation
      北京, 中国
    • Year and Date
      2011-11-01
  • [Presentation] Antibody Engineering as an Interface Molecule for Inorganic Nano-materials, MRS workshop2011

    • Author(s)
      Mitsuo Umetsu, Takamitsu Hattori, Takanari Togashi, Tadafumi Adschiri, Izumi Kumagai
    • Organizer
      Directed Self-Assembly of Materials Workshop
    • Place of Presentation
      ナッシュビル, 米国
    • Year and Date
      2011-09-29
  • [Presentation] Nanoclustering design for the construction of artificial cellulosomes : High enhancement of cellulolytic enzyme activity by clustering on nanoscaffolds2011

    • Author(s)
      Mitsuo Umetsu, Do-Myoung Kim, Kyo Takai, Takashi Matsuyama, Nobuhiro Ishida, Haruo Takahashi, Ryutaro Asano, Izumi Kumagai
    • Organizer
      2011 E-MRS
    • Place of Presentation
      ニース, フランス
    • Year and Date
      2011-05-12
  • [Presentation] Antibody Engineering as a Novel Interface Molecule for Inorganic Materials2011

    • Author(s)
      Mitsuo Umetsu, Takamitsu Hattori, Satoshi Ohara, Takeshi Nakanishi, Izumi Kumagai
    • Organizer
      American Chemical Society Spring 2011 National Meeting
    • Place of Presentation
      アナハイム, 米国
    • Year and Date
      2011-03-29
  • [Presentation] 低エネルギー負荷社会を指向した蛋白質デザイン2010

    • Author(s)
      梅津光央
    • Organizer
      化学系学協会東北大会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-09-26
  • [Presentation] 無機結晶面を識別する抗体の建設的な作り方2010

    • Author(s)
      梅津光央, 服部峰充, 冨樫貴成, 阿尻雅文, 熊谷泉
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-25
  • [Presentation] 抗体分子を利用した異種材料間インターフェイス開発:バイオイメージングへの展開2010

    • Author(s)
      梅津光央, 服部峰充, 広瀬達也, 阿尻雅文, 熊谷泉
    • Organizer
      第42回化学工学会秋季大会
    • Place of Presentation
      京都
    • Year and Date
      2010-09-07
  • [Presentation] 「ナノ」の視点から考える蛋白質とナノ材の接点2010

    • Author(s)
      梅津光央
    • Organizer
      化学生命工学談話会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-31
  • [Presentation] Antibody Engineering as a Novel Interface Molecule for Inorganic Materials2010

    • Author(s)
      Mitsuo Umetsu, Takamitsu Hattori, Takanari Togashi, Takuya Hirose, Izumi Kumagai
    • Organizer
      2010 E-MRS
    • Place of Presentation
      ストラスブール, フランス
    • Year and Date
      2010-06-07
  • [Presentation] The generation of the antibodies with high affinity for inorganic nanomaterials by peptide-grafting and molecular evolutionary methods2010

    • Author(s)
      Mitsuo Umetsu, Takamitsu Hattori, Satoshi Ohara, Takeshi Nakanishi, Izumi Kumagai
    • Organizer
      2010 MRS Spring Meeting
    • Place of Presentation
      サンフランシスコ, 米国
    • Year and Date
      2010-04-06
  • [Presentation] ナノ材を抗原とするペプチド・抗体:発見とナノバイオ展開2010

    • Author(s)
      梅津光央
    • Organizer
      (社)表面技術協会第35回「ナノテク部会」研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-01-21
  • [Presentation] Protein engineering for bioimaging2010

    • Author(s)
      Mitsuo Umetsu
    • Organizer
      3rd International Symposium on Bioimaging
    • Place of Presentation
      岡崎
    • Year and Date
      2010-01-19
  • [Presentation] dentification of Induim Tin Oxide interfacial-specific peptides by phage display system2009

    • Author(s)
      広瀬達也, 梅津光央, 熊谷泉
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
  • [Presentation] 金属材料表面特異的抗体から発想されるナノ素材機能化2009

    • Author(s)
      服部峰充, 梅津光央, 中西猛, 熊谷泉
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-24
  • [Book] 『究極のかたちをつくる』第3章3バイオミネラリゼーションによるかたちづくり2009

    • Author(s)
      梅津光央
    • Total Pages
      164-173
    • Publisher
      日刊工業新聞社
  • [Remarks]

    • URL

      http://www.che.tohoku.ac.jp/~kuma/index.htm

URL: 

Published: 2013-07-31  

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