2010 Fiscal Year Final Research Report
Estimate of the number of MHC haplotypes of a common marmoset
| Project/Area Number |
21700446
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Laboratory animal science
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
TAKABAYASHI Shuji Hamamatsu University School of Medicine, 医学部附属動物実験施設, 助教 (70372521)
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| Project Period (FY) |
2009 – 2010
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| Keywords | コモンマーモセット / 主要組織適合複合体(MHC) |
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| Research Abstract |
This study aims at establishing the PCR-based major histocompatability complex (MHC) genotyping methods for the common marmosets and identifying genetic polymorphism of MHC class I and class II gene in individual marmosets. I present here a first step in the molecular characterization of the common marmoset's MHC class II genes, Caja-DQA1、DQB1、DRA1 and DRB1*03 by nucleotide sequence analysis of the polymorphic exon 2 segments. Next step, I analyzed the molecular characterization of the common marmoset's MHC class I, Caja-G gene by nucleotide sequence analysis of the polymorphic exon 3 segments.
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