2010 Fiscal Year Final Research Report
Development of mesoporous silica for removal of middle molecule uremic toxins
| Project/Area Number |
21760527
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Inorganic materials/Physical properties
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
HOSHIKAWA Yasuto Tohoku University, 多元物質科学研究所, 助教 (90527839)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Keywords | ナノ材料 / 生体材料 / メソポーラスシリカ / 炭素被覆 |
|---|
| Research Abstract |
Selective removal of middle molecule uremic toxins is difficult in a current hemodialysis membrane. Mesoporous silica nanoparticles (MSNs) are promising as superior adsorbent for specific middle molecule with highly selectivity. Expansion of mesopore (over 6nm, the size is well suited to absorbing middle molecule) in MSNs was achieved by adding 1,3,5-trimethylbenzene and incorporating aminopropyl group in silica structure, and the silica surface of MSNs was coated by carbon thin layer (under 1nm) to improve blood compatibility and durability.
|
Research Products
(14 results)
-
-
-
-
-
[Presentation] カーボンナノ試験管のナノ空間内でのDNA濃縮2010
Author(s)
干川康人, 寒河江拓也, 菅野康之, 折笠広典, Somlak Ittisanronnach, 井本修平, 和田健彦, 永次史, 京谷隆
Organizer
2010高分子・ハイブリッド材料研究センター若手フォーラム
Place of Presentation
東北大学片平さくらホール(仙台)
Year and Date
2010-12-06
-
-
-
-
-
-
-
-
-
