2010 Fiscal Year Final Research Report
Development of environmentally friendly organometallic synthetic method for nitrogen containing heterocycles and its application to drug discovery
| Project/Area Number |
21790003
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemical pharmacy
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| Research Institution | Hokkaido University |
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Principal Investigator |
ARISAWA Mitsuhiro Hokkaido University, 大学院・薬学研究院, 准教授 (40312962)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 有機化学 / 合成化学 / 創薬科学 / 触媒・化学プロセス / 環境技術 |
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| Research Abstract |
Development of novel catalyst, reaction, and synthetic method for drug discovery was succeeded. Thus, sulfur-modified Au-supported Pd, ring-closing metathisis/oxidation, and cycloisomerization of ene and 1,3-diene were developed for drug library synthesis and discovery of selective MAO inhibitory agents.
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Research Products
(39 results)
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[Journal Article] Hard X-ray Photoemission Spectroscopic Investigation of Palladium Catalysts immobilized on a GaAs(001) Surface2010
Author(s)
Masahiko Shimoda, Tomoya Konishi, Kazuishi Tateishi, Takuya Toujyou, Shiro Tsukamoto, Nagatoshi Nishiwaki, Mitsuhiro Arisawa, Naoyuki Hoshiya, Satoshi Shuto, Nobuhiro Isomura, Hiroshi Yokota, Yuzo Furukawa, Kanji Iizuka, Tadashi Ogiwara, Yosuke Isozaki, Yoshiyuki Yamashita, Hideki Yoshikawa, Shigeru Ueda, Kazuto Kobayashi
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Journal Title
J.Appl.Phy. 108
Pages: "024309-1"-"024309-5"
Peer Reviewed
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