2010 Fiscal Year Final Research Report
Regulation of cytotoxic T lymphocyte activities by MHC class I-binding receptors.
| Project/Area Number |
21790458
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Immunology
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| Research Institution | Tohoku University |
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Principal Investigator |
ENDO Shota Tohoku University, 加齢医学研究所, 助教 (70466580)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 免疫制御 / 移植免疫 / 腫瘍免疫 / 細胞傷害性T細胞 / 樹状細胞 |
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| Research Abstract |
MHC class I-binding receptors regulate cytotoxic T lymphocyte activities, which cells are indispensable in controlling tumor and transplant rejection. In this study, I have clarified the molecular mechanism of the regulation system controlled by the MHC class I-binding receptors. The findings will provide a novel strategy for regulating cytotoxic T lymphocyte-mediated immunity and diseases.
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