2010 Fiscal Year Final Research Report
Control of tumor formation after transplantation in regenerative therapy with genetic engineering methods
| Project/Area Number |
21790528
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied pharmacology
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
TAHARA Tsuyoshi The Institute of Physical and Chemical Research, 分子プローブ機能評価研究チーム, 研究員 (20419708)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 再生医療 / がん / HSV-TK |
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| Research Abstract |
Gene therapy and cell transplantation therapy is expected to be a breakthrough for treating neurodegenerative disorders, such as Parkinson's and Alzheimer's disease. In this study, I could isolate the tumor- or non-differentiated cell-specific promoter region from Oct3/4 gene promoter and make the GFP expression vector, which works only in non-differentiated cell, such as mouse embryonic EB5 cell but not mouse fibroblast Balb/3T3b cells.
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