2010 Fiscal Year Final Research Report
Alleviative effects of food components on male reproductive toxicity induced by diesel exhaust particles.
| Project/Area Number |
21790554
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Hygiene
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| Research Institution | Aomori University of Health and Welfare |
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Principal Investigator |
IZAWA Hiromi Aomori University of Health and Welfare, 健康科学部, 講師 (20315534)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 環境 / 食品 / 衛生 |
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| Research Abstract |
BALB/ c mice (5 week age) were fed diets which contained 0.01, 0.1 and 1% quercetin respectively, and 0.05mg/ml diesel exhaust particle (DEP) suspension or vehicle was instilled through an intratracheal cannula under anesthesia with halothane twice per week for 6 weeks.
Plasma concentrations of testosterone in the DEP-treated group and the DEP-treated+1% Quercetin-fed group were significantly lower than in the vehicle-treated group. Thisresult indicated that DEP decreased the plasma concentrations of testosterone. Low andmiddle concentration of quercetin diets may alleviate the male reproductive toxicity induced by DEP, but high concentration may not.
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Research Products
(6 results)
