2011 Fiscal Year Final Research Report
Association of adiponectin polymorphism with cord blood adiponectin concentrations and intrauterine growth
| Project/Area Number |
21791032
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | University of Tsukuba |
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Principal Investigator |
SAITO Makoto 筑波大学, 医学医療系, 講師 (80535021)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 新生児医学 |
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| Research Abstract |
We found that the neonates carrying the G allele of rs266729 had a significantly greater birth weight SD score than those homozygous for the C allele. However, this difference wasn't significant after adjustment for cord blood adiponectin. The rs266729 SNP was strongly associated with cord blood adiponectin. This association remained after adjustment for birth weight SD score. Our results suggest that the influence of the rs266729 SNP in ADIPOQ on birth weight may be dependent on circulating adiponectin.
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[Journal Article] Association of adiponectin polymorphism with cord blood adiponectin concentrations and intrauterine growth2012
Author(s)
Saito M, Kamoda T, Nishimura K, Miyazono Y, Kanai Y, Kato Y, Iwabuchi A, Fukushima H, Hamada H, Arinami T, Sumazaki R, Noguchi E
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Journal Title
J Hum Genet
Volume: 57(2)
Pages: 109-14
DOI
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