2010 Fiscal Year Final Research Report
Development of Novel Neovascularization-Imaging Agent for PET.
| Project/Area Number |
21791163
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | Hokkaido University |
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Principal Investigator |
AITA Kazuki Hokkaido University, アイソトープ総合センター, 助教 (80456839)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 造影剤 / PET / 標識化 |
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| Research Abstract |
The aim of this study is "Development of Novel PET(Positron Emission Tomography) Imaging Agent for Neovascularization". And we selected thymidine phosphorilase (TP) as the neovascularization indicator. So, we designed F-TPI as the novel neovascularization-imaging agent for PET. F-TPI has urasil structure and (radio) fluorine atom. And we succeeded in the synthesis of the precursor of F-TPI.
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